Results 31 to 40 of about 42,311 (246)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Response characteristics of methane–air and propane–air premixed flames to sinusoidal oscillations in equivalence ratio (Effects of Lewis number and preferential diffusion)

Journal of Thermal Science and Technology
Flames propagate in mixture flows with inhomogeneous concentration distributions in practical combustors, such as gasoline direct-injection engines and gas turbine engines. Clarifying the effect of fuel-type differences on the response characteristics of
Yosuke SUENAGA, Hideki YANAOKA, Shohei SEO, Komei NIWATA   +3 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Temperature-dependent in-situ LEIS measurement of W surface enrichment by 250 eV D sputtering of EUROFER

Nuclear Materials and Energy, 2018
Tungsten surface enrichment of EUROFER steel by 250 eV deuterium sputtering is in-situ measured using low energy He+ ion scattering spectroscopy. The samples are irradiated at various temperatures between 300 K and 800 K with a deuterium atom flux of 2 × 
H.R. Koslowski, S.R. Bhattacharyya, P. Hansen, Ch. Linsmeier, M. Rasiński, P. Ström   +5 more
doaj   +1 more source

Oxidation of Au/Ag films by oxygen plasma: phase separation and generation of nanoporosity

Beilstein Journal of Nanotechnology, 2020
The oxidation of Au/Ag alloy thin films using radio-frequency oxygen plasma was studied in this work. It was demonstrated that there is a phase separation occurring between silver and gold.
Abdel-Aziz El Mel, Said A. Mansour, Mujaheed Pasha, Atef Zekri, Janarthanan Ponraj, Akshath Shetty, Yousef Haik   +6 more
doaj   +1 more source

Condensability sieving porous coordination polymer membranes for preferential permeation of C1–C4 alkanes over H2

Advanced Membranes, 2022
Refinery gas contains abundant H2 and a small amount of C1–C4 hydrocarbons. Here, we propose a condensability sieving strategy to realize preferential permeation of hydrocarbons over H2 by developing halogen-induced porous coordination polymer (PCP ...
Xuemeng Jia, De Ao, Zibo Yang, Zhihua Qiao, Yuxiu Sun, Michael D. Guiver, Chongli Zhong   +6 more
doaj   +1 more source

LES flamelet modeling of hydrogen combustion considering preferential diffusion effect

International Journal of Hydrogen Energy, 2023
A flamelet-generated manifold (FGM) method that explicitly considers the preferential diffusion effect, referred to as FGM-PD method, is employed for large-eddy simulations (LESs) of a lean-premixed H2/air low-swirl lifted flame, and the validity is examined by comparing with the experiment. First, the applicability of the FGM-PD method is investigated
Reo Kai, Taiki Tokuoka, Jun Nagao, Abhishek Lakshman Pillai, Ryoichi Kurose   +4 more
openaire   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Numerical Investigation on the Flame Characteristics of Lean Premixed Methane Flame Piloted with Rich Premixed Flame

Energies
The introduction of the pilot flame can stabilize the lean premixed flame and promote its industrial application. However, the interaction mechanism between the pilot and main flames is complicated.
Lili Zhang, Yongzhang Cui, Pengfei Yin, Wenlong Mao, Pengzhao Zhang   +4 more
doaj   +1 more source