Results 41 to 50 of about 48,803 (218)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Achieving excellent oxidation performance of laser additively manufactured Inconel 718

Journal of Materials Research and Technology
A synergistic strategy combining quasi-continuous-wave (QCW) laser in-process control with post-deposition homogenization treatment is proposed to tailor the dendritic structure of additively manufactured Inconel 718 for oxidation performance improvement.
Yanqin Li, Guoyun Luo, Lijun Song
doaj   +1 more source

Experimental and simulation-based investigation of He, Ne and Ar irradiation of polymers for ion microscopy

Beilstein Journal of Nanotechnology, 2016
Secondary ion mass spectrometry (SIMS) on the helium ion microscope (HIM) promises higher lateral resolution than on classical SIMS instruments. However, full advantage of this new technique can only be obtained when the interaction of He+ or Ne+ primary
Lukasz Rzeznik, Yves Fleming, Tom Wirtz, Patrick Philipp   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Hydrogen addition and preferential diffusion effects on swirling boundary layer flashback

Case Studies in Thermal Engineering
The preferential diffusion (PD) is significant for the hydrogen fuel and revealing its effects on flashback is significant to improve the stability of the lean-premixed gas turbine combustors enriched with hydrogen.
Weijie Zhang, Haifeng Liu, Xinyuan Cao, Pengxiang Song, Meng Zhang, Chengyu Chi, Jinhua Wang   +6 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Probing solid-state diffusion and its synergistic role with preferential oxidation in enhancing the ablation performance of multiphase multicomponent carbide

Journal of Advanced Ceramics
Multiphase multicomponent ultrahigh-temperature ceramics (UHTCs) hold great promise for achieving better ablation performance because of their broader structure and compositional tunability.
Ziming Ye, Jiao Hu, Yi Zeng, Xiang Xiong, Nan Ye, Haiou Zhuo, Ben Huang, Jiancheng Tang, Huilin Lun   +8 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Comparison on the coercivity enhancement of sintered NdFeB magnets by grain boundary diffusion with low-melting (Tb, R)75Cu25 alloys (R= None, Y, La, and Ce)

AIP Advances, 2019
A significant coercivity enhancement of the commercial NdFeB magnets with the magnetic properties of (BH)max = 48.4 MGOe and iHc = 17.5 kOe through grain boundary diffusion (GBD) with low-melting Tb55R20Cu25 alloys is demonstrated.
Y. J. Wong, H. W. Chang, Y. I. Lee, W. C. Chang, C. H. Chiu, C. C. Mo   +5 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source