Results 61 to 70 of about 45,302 (261)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Silicon regulation of the interface microstructure and shear strength of rheological cast-rolling aluminum/steel composite plates

Journal of Materials Research and Technology
This study reports the preparation of medium-thickness aluminum/steel composite plates with different diffusion layers using rheological cast-rolling technology.
Jin Qiu, Yuandong Li, Xiaomei Luo, Hongwei Zhou, Chi Cao, Guangli Bi   +5 more
doaj   +1 more source

Analysis of the Numerical Diffusion in Anisotropic Mediums: Benchmarks for Magnetic Field Aligned Meshes in Space Propulsion Simulations

Applied Sciences, 2016
This manuscript explores numerical errors in highly anisotropic diffusion problems. First, the paper addresses the use of regular structured meshes in numerical solutions versus meshes aligned with the preferential directions of the problem.
Daniel Pérez-Grande, Oscar Gonzalez-Martinez, Pablo Fajardo, Eduardo Ahedo   +3 more
doaj   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Improving Discrete Diffusion Models via Structured Preferential Generation

CoRR
10 pages, 7 ...
Severi Rissanen, Markus Heinonen, Arno Solin   +2 more
openaire   +2 more sources

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Direct observation of substitutional and interstitial dopant diffusion in oxide grain boundary

Nature Communications
Grain boundaries (GBs) serve as fast diffusion paths for dopant atoms, and the segregated dopants can significantly alter the materials’ properties. However, the exact mechanism of fast dopant diffusion along the GBs, particularly at atomic scale, is ...
Toshihiro Futazuka, Ryo Ishikawa, Tatsuya Yokoi, Katsuyuki Matsunaga, Naoya Shibata, Yuichi Ikuhara   +5 more
doaj   +1 more source

Information Diffusion and Preferential Attachment in a Network of Large Language Models

2025 IEEE 64th Conference on Decision and Control (CDC)
This paper models information diffusion in a network of Large Language Models (LLMs) that is designed to answer queries from distributed datasets, where the LLMs can hallucinate the answer. We introduce a two-time-scale dynamical model for the centrally administered network, where opinions evolve faster while the network's degree distribution changes ...
Adit Jain, Vikram Krishnamurthy, Yiming Zhang   +2 more
openaire   +2 more sources

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source