Annals of Neurology, EarlyView.Objective Biomarkers of disease pathogenesis are critically needed for amyotrophic lateral sclerosis (ALS) to facilitate diagnosis and patient stratification into appropriate therapeutic trials. Proteomic studies offer significant potential to advance this, but reproducibility across laboratories is a key component toward identifying protein changes ...
Gabrielle L. Adler +2 more
wiley +1 more source
5-HT2 Receptor Regulation of Extracellular GABA Levels in the Prefrontal Cortex [PDF]
, 1999 Walid Abi‐Saab +3 more
openalex +1 more source
Annals of Neurology, EarlyView.Objectives Prospective studies demonstrated that essential tremor is a risk factor for Parkinson's disease. Identifying clinical markers for conversion from essential tremor to essential tremor‐Parkinson's disease would be of considerable value. Rest tremor can be present in advanced essential tremor and may be a harbinger of conversion. We examined (1)
Elan D. Louis +3 more
wiley +1 more source
Glutamatergic Regulation of Basal and Stimulus‐Activated Dopamine Release in the Prefrontal Cortex [PDF]
, 1998 Ryuichi Takahata, Bita Moghaddam
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Mapping Postictal Aphasia through Signal Complexity: A Stereo‐Electroencephalography Study
Annals of Neurology, EarlyView.Objective The postictal period provides an opportunity to investigate the pathophysiology underlying aphasia and recovery following epileptic seizures. This study examines postictal aphasia in stereo‐electroencephalography (SEEG)‐explored patients to identify brain regions associated with task‐specific language deficits using signal complexity analysis.
Ionuț‐Flavius Bratu +6 more
wiley +1 more source
Electrical Stimulation of Rat Medial Prefrontal Cortex Enhances Forebrain Serotonin Output Implications for Electroconvulsive Therapy and Transcranial Magnetic Stimulation in Depression [PDF]
, 1999 Georg Juckel +2 more
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Annals of Neurology, EarlyView.Objective The objective of this study was to investigate the relationships among subthalamic nucleus (STN) activity, gait initiation (GI), and freezing of gait (FOG) in patients with Parkinson's disease (PD). Methods We recorded GI and STN local field potentials (LFPs) via externalized cables in 38 patients with PD (35 reporting FOG in daily life ...
Antoine Collomb‐Clerc +12 more
wiley +1 more source
Errors of Memory-Guided Saccades in Humans With Lesions of the Frontal Eye Field and the Dorsolateral Prefrontal Cortex [PDF]
, 1999 Christoph J. Ploner +4 more
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Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases
Annals of Neurology, EarlyView.Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich +20 more
wiley +1 more source
Chronic Nicotine Enhances Basal and Nicotine-Induced Fos Immunoreactivity Preferentially in the Medial Prefrontal Cortex of the Rat [PDF]
, 1997 Margret Nisell
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