Results 141 to 150 of about 591,591 (296)
Zuranolone: A case study in (regulatory) rush to judgement?
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
Dynamic gating in the nucleus accumbens: Behavioral state-dependent synchrony with the prefrontal cortex and hippocampus [PDF]
Contextual and sensory information, goals, and the motor plan to achieve them are integrated in the nucleus accumbens (NA). Although this integration needs flexibility to operate in a variety of environments, models of NA function rarely consider ...
Rifat J. Hussain +2 more
core
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen +4 more
wiley +1 more source
Prefrontal Planning Latency Associated With Age and Serological Evidence of Microbial Exposure
Planning latency versus age by group. Scatterplot showing individual observations (n = 53) stratified by fibromyalgia status. LOESS smoothing curves with 95% confidence intervals (shaded regions) illustrate the relationship within each group. Overall, rₛ = 0.394 (p = 0.003).
Basant K. Puri +4 more
wiley +1 more source
Abstract The prefrontal cortex receives perceptual information from the temporal and parietal cortices, and is in a position to perform ‘off-line’ processing, including holding items in a short-term memory when the items are no longer present in the input processing streams.
openaire +1 more source
ObjectiveTo explore the characteristics of functional connectivity in the prefrontal cortex of children with attention deficit hyperactivity disorder (ADHD) at rest and the level of brain functional activation during the Go/No-go task using functional ...
WANG Jing +7 more
doaj
ABSTRACT Objective Eating disorders (EDs) are characterized by high rates of psychiatric comorbidity and suboptimal treatment outcomes. There remain critical gaps in research, including the exploration of effective transdiagnostic interventions. This forum article examines the potential of psilocybin treatment (PT) as a transdiagnostic intervention for
Elena Koning +2 more
wiley +1 more source
ABSTRACT Objective Early adolescence is characterized by the onset of mental health problems, including eating pathology (e.g., body image concerns, restrictive eating). Inhibitory control (IC) and reward sensitivity (RS) are two key traits that have been implicated in the development of eating problems.
Jaron X. Y. Tan, Lisa Brooks, Pan Liu
wiley +1 more source
Entwicklungsneuroplastizität im Hippokampus : ein Zusammenspiel limbo-präfrontaler Schaltkreise [PDF]
Schäfers ATU. Developmental neuroplasticity in the hippocampus : an interplay of prefrontal-limbic circuits. Bielefeld (Germany): Bielefeld University; 2009.Neuroplastizität, die Fähigkeit des Gehirns, auf umweltbedingte und intrinsiche Stimulation zu ...
Schäfers, Andrea T. U.
core

