Results 121 to 130 of about 591,591 (296)

The prefronto-temporal circuit for the controlled retrieval of information from memory

Dialogues in Clinical Neuroscience & Mental Health, 2018
The findings from a series of studies on patients with damage to the prefrontal cortex, as well as experiments with functional neuroimaging on normal subjects, have highlighted the specialized role of the ventral part of the lateral prefrontal cortex in ...
Michael Petrides
doaj   +1 more source

Individual Differences in Amygdala and Ventromedial Prefrontal Cortex Activity are Associated with Evaluation Speed and Psychological Well-being [PDF]

, 2007
Using functional magnetic resonance imaging, we examined whether individual differences in amygdala activation in response to negative relative to neutral information are related to differences in the speed with which such information is evaluated, the ...
Cory A. Jackson, Alexander, Andrew L., Johnstone, Tom, Carien M. van Reekum, Andrew L. Alexander, Urry, Heather L., Tom Johnstone, Hillary S. Schaefer, Van Reekum, Carina Marije, Corrina J. Frye, Richard J. Davidson, Thurow, Marchell E., Schaefer, Hillary S., Frye, Corrina J., Heather L. Urry, Marchell E. Thurow, Davidson, Richard J., Jackson, Cory A.   +17 more
core   +1 more source

CausalCellInfer: Prioritizing Cell‐Type‐Specific Disease Associations From Genetically Predicted Transcriptomes in Biobank Cohorts

Advanced Science, EarlyView.
Bulk and genotype‐imputed transcriptomes obscure the cellular drivers of complex disease. CausalCellInfer resolves them by integrating invariant marker selection, deep learning deconvolution, and regularized matrix completion. Applied to ∼500 000 UK Biobank participants across 29 traits, it uncovers hallmark cell‐type proportion shifts, including ...
Liangying Yin, Yujia Shi, Ruoyu Zhang, Yong Xiang, Jinghong Qiu, Pak‐Chung Sham, Hon‐Cheong So   +6 more
wiley   +1 more source

Altered resting-state functional connectivity of the frontal-striatal reward system in social anxiety disorder.

PLoS ONE, 2015
We investigated differences in the intrinsic functional brain organization (functional connectivity) of the human reward system between healthy control participants and patients with social anxiety disorder.
Joshua Manning, Gretchen Reynolds, Zeynep M Saygin, Stefan G Hofmann, Mark Pollack, John D E Gabrieli, Susan Whitfield-Gabrieli   +6 more
doaj   +1 more source

Prefrontal cortex lesions augment the location-related firing properties of area TE/perirhinal cortex neurons in a working memory task

, 2001
It has previously been proposed that prefrontal cortex may have some role in keeping temporal cortex-based representations 'on-line' during a working memory task.
Bilkey D. K., Zironi I., Aicardi G., Iacovelli P., Liu P., I. Zironi   +5 more
core   +1 more source

Disrupted Top‐Down Modulation as a Mechanism of Impaired Multisensory Processing in Autistic Children

Advanced Science, EarlyView.
In this work, we show that multisensory integration in autistic children is characterized by attenuated ERP responses and α‐band desynchronization, together with reduced theta‐band communication between parieto‐occipital and frontal regions. The intermediate neural profile observed in unaffected siblings raises the possibility that altered cortical ...
Theo Vanneau, John J. Foxe, Shlomit Beker, Sophie Molholm   +3 more
wiley   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source

Prefrontal hemodynamic responses to astringency aftertaste across alcoholic and alcohol-free matrices: A functional near-infrared spectroscopy study

Current Research in Food Science
Astringency is an important mouthfeel attribute in many beverages, yet its neurophysiological correlates remain poorly understood. It also remains unclear how beverage matrix shapes frontal hemodynamic responses to astringency over time.
Xin Chen, Ran Tao, Xue Gong, Hang Liang, Yujia Yang, Fengnan Niu, Lingqi Li, Yang Ye, Dejing Xin, YiDi Yang, Siying Liu, Peng Wang   +11 more
doaj   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Confabulation: damage to a specific inferior medial prefrontal system [PDF]

, 2007
Confabulation, the pathological production of false memories, occurs following a variety of aetiologies involving the frontal lobes, and is frequently held to be underpinned by combined memory and executive deficits. However, the critical frontal regions
Cipolotti, L., Yousry, T.A., Shallice, T., Turner, M.S.   +3 more
core