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The prefrontal cortex in sleep
Trends in Cognitive Sciences, 2002Experimental data indicate a role for the prefrontal cortex in mediating normal sleep physiology, dreaming and sleep-deprivation phenomena. During nonrandom-eye-movement (NREM) sleep, frontal cortical activity is characterized by the highest voltage and the slowest brain waves compared to other cortical regions.
Amir Muzur +2 more
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Prefrontal cortex and depression
Neuropsychopharmacology, 2021The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in major depressive disorder (MDD). Although functional and structural PFC abnormalities have been reported in both individuals with current MDD as well as those at increased vulnerability to MDD, this information has not translated into better treatment and ...
Diego A. Pizzagalli, Angela C. Roberts
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Evolution of prefrontal cortex
Neuropsychopharmacology, 2021Subdivisions of the prefrontal cortex (PFC) evolved at different times. Agranular parts of the PFC emerged in early mammals, and rodents, primates, and other modern mammals share them by inheritance. These are limbic areas and include the agranular orbital cortex and agranular medial frontal cortex (areas 24, 32, and 25).
Todd M, Preuss, Steven P, Wise
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Neuropsychopharmacology, 2021
Obsessive Compulsive Disorder (OCD) is a highly prevalent and severe neuropsychiatric disorder, with an incidence of 1.5-3% worldwide. However, despite the clear public health burden of OCD and relatively well-defined symptom criteria, effective treatments are still limited, spotlighting the need for investigation of the neural substrates of the ...
Susanne E, Ahmari, Scott L, Rauch
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Obsessive Compulsive Disorder (OCD) is a highly prevalent and severe neuropsychiatric disorder, with an incidence of 1.5-3% worldwide. However, despite the clear public health burden of OCD and relatively well-defined symptom criteria, effective treatments are still limited, spotlighting the need for investigation of the neural substrates of the ...
Susanne E, Ahmari, Scott L, Rauch
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The Neuropsychology of the Prefrontal Cortex
Archives of Neurology, 1993Single photon emission computed tomography with the xenon inhalation technique is used to compare activation of regional cerebral blood flow in frontal brain regions during the performance of four widely used neuropsychological tests: the Continuous Performance Test, the Wisconsin Card Sorting Test, the Tower of London, and Porteus Mazes.
K, Rezai +5 more
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2010
The prefrontal cortex (PFC) circuits are characterized by several distinct features. First, the input–output connections of a PFC circuit with the rest of the brain are extraordinarily extensive. In the primates, pyramidal neurons in PFC are greatly more spinous than in the primary sensory areas, so they have a much larger capacity for synaptic ...
R. Hamish McAllister-Williams +199 more
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The prefrontal cortex (PFC) circuits are characterized by several distinct features. First, the input–output connections of a PFC circuit with the rest of the brain are extraordinarily extensive. In the primates, pyramidal neurons in PFC are greatly more spinous than in the primary sensory areas, so they have a much larger capacity for synaptic ...
R. Hamish McAllister-Williams +199 more
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2006
Abstract This chapter describes the isotope injections that were placed in the prefrontal cortex of four rhesus monkeys. It analyzes the resulting association, striatal, commissural, and subcortical fiber trajectories, as well as the cortical and subcortical terminations. The injections were in the medial surface of the prefrontal cortex
Jeremy D. Schmahmann, Deepak N. Pandya
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Abstract This chapter describes the isotope injections that were placed in the prefrontal cortex of four rhesus monkeys. It analyzes the resulting association, striatal, commissural, and subcortical fiber trajectories, as well as the cortical and subcortical terminations. The injections were in the medial surface of the prefrontal cortex
Jeremy D. Schmahmann, Deepak N. Pandya
+5 more sources
2021
Abstract The key to the granular prefrontal (PF) cortex is that it sits at the top of the sensory processing hierarchy, the motor hierarchy, and the outcome hierarchy. This means that it is a position to learn abstract task rules. These relate to conditional tasks that involve sequences, associations, and attentional performance. Because
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Abstract The key to the granular prefrontal (PF) cortex is that it sits at the top of the sensory processing hierarchy, the motor hierarchy, and the outcome hierarchy. This means that it is a position to learn abstract task rules. These relate to conditional tasks that involve sequences, associations, and attentional performance. Because
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1998
At this point in the description of this conceptual theory of higher-level brain function, one must ask a very important question: what new functional capabilities evolved with the creation of the limbic system level? The answer would be quite clear. The system acquired the ability to actively learn and perform discrete multistep control by utilizing ...
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At this point in the description of this conceptual theory of higher-level brain function, one must ask a very important question: what new functional capabilities evolved with the creation of the limbic system level? The answer would be quite clear. The system acquired the ability to actively learn and perform discrete multistep control by utilizing ...
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Prefrontal Cortex, Structural Analysis: Segmenting the Prefrontal Cortex
American Journal of Psychiatry, 2004Robert W, Buchanan, Godfrey, Pearlson
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