Results 11 to 20 of about 879,620 (403)

Prefrontal Cortex Activation and Young Driver Behaviour: A fNIRS Study. [PDF]

PLoS ONE, 2016
Road traffic accidents consistently show a significant over-representation for young, novice and particularly male drivers. This research examines the prefrontal cortex activation of young drivers and the changes in activation associated with ...
Hannah J Foy, Patrick Runham, Peter Chapman   +2 more
doaj   +7 more sources

The whole prefrontal cortex is premotor cortex [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2021
We propose that the entirety of the prefrontal cortex (PFC) can be seen as fundamentally premotor in nature. By this, we mean that the PFC consists of an action abstraction hierarchy whose core function is the potentiation and depotentiation of possible action plans at different levels of granularity.
Justin M. Fine, Benjamin Y. Hayden
openaire   +3 more sources

The role of the medial prefrontal cortex in cognition, ageing and dementia

Brain Communications, 2021
Humans require a plethora of higher cognitive skills to perform executive functions, such as reasoning, planning, language and social interactions, which are regulated predominantly by the prefrontal cortex.
D. Jobson, Y. Hase, A. Clarkson, R. Kalaria   +3 more
semanticscholar   +1 more source

Your verbal questions beginning with 'what' will rapidly deactivate the left prefrontal cortex of listeners

Scientific Reports, 2021
The left prefrontal cortex is essential for verbal communication. It remains uncertain at what timing, to what extent, and what type of phrase initiates left-hemispheric dominant prefrontal activation during comprehension of spoken sentences.
Hirotaka Iwaki, Masaki Sonoda, Shin-ichiro Osawa, Brian H. Silverstein, Takumi Mitsuhashi, Kazushi Ukishiro, Yutaro Takayama, Toshimune Kambara, Kazuo Kakinuma, Kyoko Suzuki, Teiji Tominaga, Nobukazu Nakasato, Masaki Iwasaki, Eishi Asano   +13 more
doaj   +1 more source

Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex

Nature Neuroscience, 2020
We used the 10x Genomics Visium platform to define the spatial topography of gene expression in the six-layered human dorsolateral prefrontal cortex.
K. E. Maynard, L. Collado-Torres, L. Weber, C. Uytingco, B. Barry, S. Williams, J. L. Catallini, M. N. Tran, Z. Besich, M. Tippani, J. Chew, Y. Yin, J. Kleinman, T. Hyde, N. Rao, S. Hicks, K. Martinowich, A. Jaffe   +17 more
semanticscholar   +1 more source

Differential patterns of prefrontal MEG activation during verbal & visual encoding and retrieval. [PDF]

PLoS ONE, 2013
The spatiotemporal profile of activation of the prefrontal cortex in verbal and non-verbal recognition memory was examined using magnetoencephalography (MEG).
Garreth Prendergast, Eve Limbrick-Oldfield, Ed Ingamells, Susan Gathercole, Alan Baddeley, Gary G R Green   +5 more
doaj   +1 more source

Network based statistical analysis detects changes induced by continuous theta-burst stimulation on brain activity at rest [PDF]

, 2014
We combined continuous theta-burst stimulation (cTBS) and resting state (RS)-fMRI approaches to investigate changes in functional connectivity (FC) induced by right dorsolateral prefrontal cortex (DLPFC)-cTBS at rest in a group of healthy subjects.
Aertsen, Beckmann, Bilek, Boggio, Boggio, Calhoun, Chen, Corbetta, Damoiseaux, De Luca, Deco, Dockery, Dosenbach, D’Esposito, Eldaief, Fink, Finn, Fitzgerald, Floel, Fox, Fox, Fox, Fregni, Friston, George, George, Glahn, Grefkes, Huang, Isenberg, Jeong, Keeser, Koch, Koch, Koch, Koch, Kwon, Lee, Meinzer, Mylius, O’Reardon, O’Shea, Padberg, Pallanti, Pascual-Leone, Pena-Gomez, Pleger, Polania, Rajkowska, Rossini, Rothwell, Schutter, Smith, Thomason, van Asselen, van den Heuvel, van der Werf, Vannini, Vercammen, Wager, Zaehle, Zalesky   +61 more
core   +7 more sources

Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety

Nature Communications, 2020
Dysregulated prefrontal control over amygdala is engaged in the pathogenesis of psychiatric diseases including depression and anxiety disorders. Here we show that, in a rodent anxiety model induced by chronic restraint stress (CRS), the dysregulation ...
Wei-Zhu Liu, Wen-Hua Zhang, Zhi-Heng Zheng, Jia-Xin Zou, Xiao-Xuan Liu, Shou-He Huang, Wen-Jie You, Ye He, Jun-Yu Zhang, Xiao-Dong Wang, Bing-Xing Pan   +10 more
semanticscholar   +1 more source

Hyperactivity of medial prefrontal cortex pyramidal neurons occurs in a mouse model of early-stage Alzheimer’s disease without β-amyloid accumulation

Frontiers in Pharmacology, 2023
The normal function of the medial prefrontal cortex (mPFC) is essential for regulating neurocognition, but it is disrupted in the early stages of Alzheimer’s disease (AD) before the accumulation of Aβ and the appearance of symptoms.
Nasreen Choudhury, Lihua Chen, Lena Al-Harthi, Xiu-Ti Hu   +3 more
doaj   +1 more source

Subtle alterations in brain anatomy may change an individual's personality in chronic pain. [PDF]

PLoS ONE, 2014
It is well established that gross prefrontal cortex damage can affect an individual's personality. It is also possible that subtle prefrontal cortex changes associated with conditions such as chronic pain, and not detectable until recent advances in ...
Sylvia M Gustin, Jamie G McKay, Esben T Petersen, Chris C Peck, Greg M Murray, Luke A Henderson   +5 more
doaj   +1 more source