Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022 Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh +5 more
wiley +1 more source
Forebrain NR2B overexpression facilitating the prefrontal cortex long-term potentiation and enhancing working memory function in mice. [PDF]
PLoS ONE, 2011 Prefrontal cortex plays an important role in working memory, attention regulation and behavioral inhibition. Its functions are associated with NMDA receptors.
Yihui Cui +9 more
doaj +1 more source
Subtle alterations in brain anatomy may change an individual's personality in chronic pain. [PDF]
PLoS ONE, 2014 It is well established that gross prefrontal cortex damage can affect an individual's personality. It is also possible that subtle prefrontal cortex changes associated with conditions such as chronic pain, and not detectable until recent advances in ...
Sylvia M Gustin +5 more
doaj +1 more source
Reciprocal anatomical relationship between primary sensory and prefrontal cortices in the human brain [PDF]
, 2011 The human brain exhibits remarkable interindividual variability in cortical architecture. Despite extensive evidence for the behavioral consequences of such anatomical variability in individual cortical regions, it is unclear whether and how different ...
Kanai, Ryota +3 more
core +2 more sources
Chinese Journal of Contemporary Neurology and Neurosurgery, 2018 Objective To investigate the changes of cerebral cortical thickness in patients with end-stage renal disease (ESRD) and the relationship between cortical thickness and kidney function.
Jian-wei DONG +5 more
doaj +1 more source
Reduction in Phencyclidine Induced Sensorimotor Gating Deficits in the Rat Following Increased System Xc − Activity in the Medial Prefrontal Cortex [PDF]
, 2013 Rationale: Aspects of schizophrenia, including deficits in sensorimotor gating, have been linked to glutamate dysfunction and/or oxidative stress in the prefrontal cortex. System xc −, a cystine–glutamate antiporter, is a poorly understood mechanism that
A Araque +81 more
core +2 more sources
When planning fails: Individual differences and error-related brain activity in problem solving. [PDF]
, 2004 The neuronal processes underlying correct and erroneous problem solving were studied in strong and weak problem-solvers using functional magnetic resonance imaging (fMRI).
Halsband, U. +8 more
core +2 more sources
Frontiers in Psychiatry, 2012 The prefrontal cortex is involved in mood and emotional processing. In patients suffering from depression, the left dorsolateral prefrontal cortex is hypoactive, while activity of the right dorsolateral prefrontal cortex is enhanced.
Michael A. Nitsche +5 more
doaj +1 more source
Strain-dependent variations in stress coping behavior are mediated by a 5-HT/GABA interaction within the prefrontal corticolimbic system [PDF]
, 2015 Background: Serotonin and γ- Aminobutyric acid (GABA) transmission is crucial in coping strategies. Methods: Here, using mice from 2 inbred strains widely exploited in behavioral neurochemistry, we investigated whether serotonin transmission in medial ...
ANDOLINA, DIEGO +3 more
core +1 more source
fNIRS-based study of prefrontal cortex activation during pelvic floor muscle contraction in women under different bladder states [PDF]
Xin yixueObjective To provide a neuroimaging basis for exploring the role of the prefrontal cortex in human urinary control function. Methods Hemodynamic data from the prefrontal cortex of the brain during the task of pelvic floor muscle contraction from 20 ...
Xu Zhengxian, Pan Weiting, Yu Cancan, Zhou Xingchen, Shi Jiao, Wang Min, Chen Shangjie
doaj +1 more source