Results 101 to 110 of about 44,821 (215)

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib, Francisco Emilio Fierro, Maria Ortega Abad, Ricardo Correa   +3 more
wiley   +1 more source

Is Hypercortisolism Treatable? Which Patients Should Be Treated and How—A Practical Guide for Clinicians

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To provide a practical guide on when to suspect endogenous hypercortisolism, how to use the overnight 1‐mg dexamethasone suppression test (DST) for targeted case‐finding, and which patients are most likely to benefit from treatment.
Juan Pablo Frias
wiley   +1 more source

The Effect of Polycythemia Vera on Pregnancy Complications. The Analysis of an American Population Database With Over 9 Million Deliveries

European Journal of Haematology, EarlyView.
ABSTRACT Objectives Polycythemia Vera (PV) is characterized by overproduction of erythrocytes, leading to a hypercoagulable state. Evidence regarding associations between PV and pregnancy outcomes is limited. The aim of our study was to provide robust evidence regarding the prevalence of pregnancy complications in women with PV.
Noah Margolese, Sarah Al‐Rayes, Shaonie Ton‐Leclerc, Ahmad Badeghiesh, Haitham Baghlaf, Michael H. Dahan   +5 more
wiley   +1 more source

A Case of a Chronic Ectopic Pregnancy in a Patient With Negative Serum β-HCG. [PDF]

Clin Case Rep
Yu S, Su X, Liu L, Wang X, Chen X.
europepmc   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

Successful live birth after interstitial ectopic pregnancy in a patient with Swyer syndrome following IVF: a case report. [PDF]

Case Rep Womens Health
Kopko J, Novikava A, Dąbrowska M, Novikava P, Niemoczyński J.   +4 more
europepmc   +1 more source

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

The FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh, Ivan Gallotta, Bolanle F. Olabiyi, Yoon Hee Choi, Sarah Inglesfield, Janet R. Kumita, Collin Y. Ewald, Della C. David   +7 more
wiley   +1 more source

Ectopic Pregnancy within a Cesarean Section Scar: An Unusual Case Report

International Medical Case Reports Journal
Emad M AL-Osail,1 Sager Almulhim2 1Department of General Surgery, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 2General Radiology, Imam Abdulrahman Bin Faisal Hospital-National Guard, Dammam, Saudi ...
AL-Osail EM, Almulhim S
doaj  

Unruptured Ectopic Pregnancy at Eight Weeks in a Woman With an Intrauterine Device. [PDF]

Cureus
Cunha Silva L, Torres MR, Araújo Pereira J, Pedro Prata J, Pinheiro P.   +4 more
europepmc   +1 more source

Experiencing and Responding to Existential Vulnerability: Navigating the Work–Fertility Treatment Interface

Gender, Work &Organization, EarlyView.
ABSTRACT The need to undergo fertility treatment to fulfill parenthood aspirations involves many challenges in professional and personal domains. Extant scholarship has tended to focus on the identity threats and individual experiences of the challenges involved, but research has not delved into the more relational experiences that may characterize ...
Céire Gilsenan, Yseult Freeney, Lisa van der Werff, Hilary O'Leary   +3 more
wiley   +1 more source