Results 31 to 40 of about 40,621 (184)

The NLS3 Motif in TPX2 Regulates Spindle Architecture in Xenopus Egg Extracts

open access: yesCytoskeleton, EarlyView.
ABSTRACT A bipolar spindle composed of microtubules and many associated proteins functions to segregate chromosomes during cell division in all eukaryotes, yet both spindle size and architecture vary dramatically across different species and cell types.
Guadalupe E. Pena   +4 more
wiley   +1 more source

Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi   +6 more
wiley   +1 more source

Ectopic pregnancy – the midwife’s role in the community [PDF]

open access: yes, 2016
Ectopic pregnancy (EP) is estimated to occur in one out of 80 women.1 Midwives and nurses are often the first port of call for a woman and therefore the importance of understanding the signs of symptoms of EP to ensure prompt referral and accurate advice
Abbott, Laura
core  

β‐Catenin localization in the ctenophore Mnemiopsis leidyi suggests an ancestral role in cell adhesion and nuclear function

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The emergence of multicellularity in animals marks a pivotal evolutionary event, which was likely enabled by molecular innovations in the way cells adhere and communicate with one another. β‐Catenin is significant to this transition due to its dual role as both a structural component in the cadherin–catenin complex and as a ...
Brian M. Walters   +5 more
wiley   +1 more source

Is induced abortion a risk factor in subsequent pregnancy? [PDF]

open access: yes, 2009
Objective: To determine whether a history of terminations of pregnancy influences subsequent pregnancies in terms of pregnancy risks, prematurity and neonatal biometrics.
Briese, Volker   +5 more
core   +1 more source

Embryonic cerebrospinal fluid pressure in fetal mice in utero: External factors pressurize the intraventricular space

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa   +2 more
wiley   +1 more source

Kohdunulkoinen raskaus-systemaattinen kirjallisuuskatsaus [PDF]

open access: yes, 2011
Tässä opinnäytetyössä tarkoituksena oli koota tieteellistä tietoa kohdunulkoisesta raskaudesta systemaattisen kirjallisuuskatsauksen avulla. Aihetta syvennettiin kolmen tutkimuskysymyksen avulla: Kuinka yleinen sairaus kohdunulkoinen raskaus on?
Itkonen, Emmi, Loimusalo, Katariina
core  

Development of node architecture and emergence of molecular organizer characteristics in the pig embryo

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The avian node is the equivalent of the amphibian Spemann's organizer, as indicated by its ability to induce a secondary axis, cellular contribution, and gene expression, whereas the node of the mouse, which displays limited inductive capacities, was suggested to be a part of spatially distributed signaling.
Braah Harmoush   +2 more
wiley   +1 more source

Activation and inhibition of Notch signaling facilitate proliferative regeneration of sensory cells in adult mice

open access: yesEye &ENT Research, EarlyView.
Abstract Due to the limited regenerative capacity in adult mammals, the loss of vestibular hair cells (HCs) leads to balance disorders. In this study, we chronologically reprogrammed adult vestibular supporting cells (SCs) via bimodal regulation of Notch signaling, mimicking dynamic changes in Notch signaling during inner ear development. We found that
Shan Zeng   +5 more
wiley   +1 more source

Imaging complications of assisted reproductive procedures [PDF]

open access: yes, 2013
The incidence of assisted conception has increased dramatically in Europe, doubling over the past decade. Assisted reproductive technology (ART) is involved in approximately 1 % of births in the developed world.
Vassallo, Pierre
core  

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