Results 61 to 70 of about 40,621 (184)
Mitochondrial tRNAGlu 14687A>G May Be A Novel Mutation for Type 2 Diabetes Mellitus
We identified a novel mitochondrial tRNAGlu 14687A>G mutation in a Han Chinese pedigree with diabetes; the m.14687A>G mutation occurred at a conserved nucleotide of tRNAGlu, which was important for tRNA structure and function. Using a cybrid cell model, we found that mutant cells exhibited much more severe mitochondrial dysfunctions than control cells,
Xiaojuan Rao+3 more
wiley +1 more source
Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy+7 more
wiley +1 more source
Abstract Background Posttraumatic stress disorder (PTSD) is associated with autonomic dysfunction as indicated by deficits in the sympathetic and parasympathetic nervous systems. These abnormalities are expressed as elevated heart rate and reduced heart rate variability (HRV), respectively.
Camila Cosmo+4 more
wiley +1 more source
Abstract Child maltreatment (CM) is associated with social problems, such as loneliness and isolation. One factor that might contribute to these problems is the tendency for individuals who have experienced CM to interpret neutral facial expressions as negative (i.e., negativity bias).
Monique C. Pfaltz+5 more
wiley +1 more source
Objectives Cesarean scar pregnancy (CSP) refers to a special type of pregnancy with a variable prognosis. We aimed to establish a prognostic classification system using ultrasound and clinical features to provide a reference for management strategies.
Xin Wang+10 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.
Luís Henrique Leão+2 more
wiley +1 more source
Prenatal Diagnosis of Horseshoe Lung: A Report of Three Cases and Review of the Literature
ABSTRACT Objective Horseshoe lung is a rare congenital malformation in which the lungs are fused by a parenchymal isthmus. The current literature is very limited regarding cases of prenatal diagnosis and their outcome. Method We retrospectively examined three cases of fetuses with horseshoe lung diagnosed antenatally in our center from 2015 to 2024 ...
Benjamin Birene+6 more
wiley +1 more source
Periodontal diseases and adverse pregnancy outcomes. Present and future
Abstract For more than two decades the possible association between periodontal diseases and adverse pregnancy outcomes has been extensively evaluated. Numerous observational, intervention, and mechanistic studies have offered valuable information on this topic.
Yiorgos A. Bobetsis+3 more
wiley +1 more source
ENT‐1‐Targeted Polymersomes to Enhance the Efficacy of Methotrexate in Choriocarcinoma Treatment
ENT‐1‐targeted stimuli‐responsive polymersomes enhance the delivery and release of MTX, as demonstrated in choriocarcinoma tumors mouse model. These targeted nanocarriers improve tumor uptake and efficiently release the drug within the tumor, highlighting their potential for enhanced chemotherapy in choriocarcinoma treatment.
Babak Mamnoon+10 more
wiley +1 more source
Two Cases of Primary Ectopic Ovarian Pregnancy [PDF]
Primary ovarian pregnancy is one of the rarest varieties of ectopic pregnancies. Patients frequently present with abdominal pain and menstrual irregularities. Intrauterine devices have evolved as probable risk factors.
Ghosal, T+3 more
core +1 more source