Results 61 to 70 of about 958,522 (307)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

MONOCHORIONIC MULTIPLE PREGNANCY

open access: yesАкушерство, гинекология и репродукция, 2016
The article describes the concept of monochorionic multiple pregnancies, the relevance and epidemiology of the topic, as well as complications in pregnancy and delivery in monochorionic twins.
N. A. Makatsariya
doaj  

Placental DEPTOR as a stress sensor during pregnancy [PDF]

open access: yes, 2011
The author(s) has paid for this article to be freely available under the terms of the Creative Commons Attribution Non-Commercial Licence (http://creativecommons.org/licenses/by-nc/2.5/) which permits unrestricted non-commercial use, distribution and ...
Gidron, Y   +4 more
core   +2 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Moninkertainen ilo : Opas vanhemmille monikkoraskaudesta ja arjesta pienokaisten kanssa [PDF]

open access: yes, 2012
Opinnäytetyön tarkoituksena oli tehdä opas monikkovanhemmille raskaus- ja lapsivuodeajasta. Vanhemmat saavat oppaan Kuopion yliopistollisen sairaalan (KYS) äitiyspoliklinikalta.
Sirviö, Johanna, Tuononen, Tiina
core  

Minimal breast milk transfer of rituximab, a monoclonal antibody used in neurological conditions. [PDF]

open access: yes, 2020
ObjectiveTo determine the transfer of rituximab, an anti-CD20 monoclonal antibody widely used for neurologic conditions, into mature breast milk.MethodsBreast milk samples were collected from 9 women with MS who received rituximab 500 or 1,000 mg ...
Anderson, Annika   +10 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

GASTRIC CANCER WITH MULTIPLE METASTASES IN PREGNANCY: A CASE REPORT

open access: yesEuromediterranean Biomedical Journal, 2019
The mortality rate in gastric cancer during pregnancy is very high, which dictates the need to research and improve the methods of early diagnosis of malignancies, as well as studying the pathogenesis of malignant tumors in pregnant women.
Borys M Filenko
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

Heterotopic Pregnancy, It is Such a Rare Finding? [PDF]

open access: yes, 2016
Heterotopic pregnancy is a multiple pregnancy with simultaneous implantation of the embryos at two or more distinct locations. Risk factors, epidemiology, signs, symptoms, sonographic findings and management options are reviewed.
Giacomello, F   +2 more
core  

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