Results 191 to 200 of about 2,658,279 (341)

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Spontaneous rupture and massive hemoperitoneum from uterine leiomyomas and adenomyosis in a nongravid and unscarred uterus

Taiwanese Journal of Obstetrics & Gynecology, 2015
Cheng-Ran Peng, Chie-Pein Chen, Kuo-Gon Wang, Liang-Kai Wang, Yi-Yung Chen, Chen-Yu Chen   +5 more
doaj   +1 more source

Phenomenological research in the field of Infant Mental Health and Early Childhood (IECMH) -A mapping review. [PDF]

Infant Ment Health J
Sorsa M, Dahl B, Røseth I.
europepmc   +1 more source

Antagonistic effect of early stage zinc on arsenic toxicity induced preterm birth during pregnancy: evidence from a rural Bangladesh birth cohort

, 2021
Yongyue Wei, Hui Huang, Yankai Xia, Liangmin Wei, Xin Chen, Ruyang Zhang, Weiwei Duan, Li Su, Mohammad L. Rahman, Mahmudur Rahman, Md. Golam Mostofa, Quazi Qamruzzaman, Wenhui Guo, Xian Sun, Hao Yu, Hongbing Shen, Zhibin Hu, David C. Christiani, Feng Chen   +18 more
openalex   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Maternal Diet Quality and Third Trimester Depression: Insights From a Nepali Birth Cohort Study. [PDF]

Matern Child Nutr
Chaudhary K, Ranade S, Paudel P, Shrestha B, Panjiyar S, Thapaliya S, Koju R, Shrestha A, Rai P, Paneru B, Shrestha N, Shrestha A, Rawal S.   +12 more
europepmc   +1 more source

GnRH analogs induce a LH peak and increase pregnancy per timed-AI in ewes

, 2023
Raquel Grande Pereira, Otávio Saraiva Pires, Clério Antônio Hoefle, Alexandro Fritzen, Giovanna Fiordalisi, Juliana Germano Ferst, Fernando Caetano de Oliveira, Arnaldo Diniz Vieira, Rafael Gianella Mondadori, Gabriel Maggi, Monique Tomazele Rovani, Bernardo Garziera Gasperin, Paulo Bayard Dias Gonçalves, Rogério Ferreira   +13 more
openalex   +2 more sources

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source