Results 51 to 60 of about 12,365 (224)

Prevalência e fatores associados à anemia em gestantes da região semi-árida do Estado de Alagoas Prevalence and factors associated with anemia in pregnant women from the semiarid region of Alagoas, Brazil

Revista Brasileira de Ginecologia e Obstetrícia, 2008
OBJETIVO: determinar a prevalência e fatores de risco associados à anemia em gestantes da região semi-árida de Alagoas. MÉTODOS: estudo de caráter transversal envolvendo amostra (n=150) obtida, considerando a prevalência estimada pela Organização Mundial
Haroldo da Silva Ferreira, Fabiana Andréa Moura, Cyro Rego Cabral Júnior   +2 more
doaj   +1 more source

Association between glucose-to-lymphocyte ratio and hematological parameters, delivery timing, and neonatal outcomes in pregnancies complicated by preterm premature rupture of membranes

Journal of Medicine and Palliative Care
Aims: To evaluate the diagnostic significance of the glucose/lymphocyte ratio (GLR) of preterm premature rupture of membranes (PPROM) and its prognostic ability in predicting adverse neonatal outcomes. Methods: A retrospective assessment was performed on 321 pregnant women who delivered at a tertiary center between January 2023 and January 2025.
Neval Çayönü Kahraman, Furkan Akın, Şevki Çelen, Ali Çağlar   +3 more
openaire   +1 more source

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

Romiplostim during pregnancy in refractory primary immune thrombocytopenia: Literature review and case series

Therapeutic Advances in Hematology
Primary immune thrombocytopenia (ITP) in pregnancy presents significant therapeutic challenges, particularly when refractory to standard treatments such as corticosteroids, intravenous immunoglobulin, and immunosuppressants.
Dina Weinstein Mezan, Efrat Shekel, Batia Roth, Yosef Kalish, Doron Kabiri   +4 more
doaj   +1 more source

Model‐Informed Evaluation of Hydroxyurea Exposure During Lactation

Clinical Pharmacology &Therapeutics, EarlyView.
Hydroxyurea is a cornerstone therapy for sickle cell anemia; however, evidence guiding its use during lactation remains limited. This study aimed to develop a population pharmacokinetic (PK) model to characterize hydroxyurea disposition in maternal plasma and breast milk, and to quantify infant exposure under clinically relevant breastfeeding scenarios.
Anhar Hosawi, Kei Irie, Min Dong, Julie Ware, Russell Ware, Tomoyuki Mizuno   +5 more
wiley   +1 more source

Maternal and Neonatal Complications Associated with Breast Cancer Systemic Treatments—A VigiBase Disproportionality Analysis Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnancy‐associated breast cancer (PrBC) presents therapeutic challenges. Understanding maternal–fetal safety of systemic anticancer therapies is critical. We performed a case/non‐case disproportionality analysis using the WHO global pharmacovigilance database up to January 2024, to evaluate maternal–fetal outcomes associated with breast cancer (BC ...
Rayan Kabirian, Floriane Jochum, Elise Dumas, Florence Coussy, Kevin Bihan, Bénédicte Lebrun‐Vignes, Barbara Pistilli, Marc‐Antoine Benderra, Lise Selleret, Laurent Chouchana, Fabien Reyal, Anne‐Sophie Hamy, Paul Gougis   +12 more
wiley   +1 more source

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

Pneumocystis Infection in Pregnant Women: A Scoping Review

Journal of Fungi
Pneumocystis jirovecii is an opportunistic fungus that causes severe pneumonia in immunosuppressed individuals. While Pneumocystis colonization, a subclinical form of infection, has been studied in different populations, its implications during pregnancy
Irene Calderón-Baturone, Rocío Salsoso, Elena Charpentier, Yaxsier de Armas, Pilar Guadix, Rubén Morilla, Enrique J. Calderón, Vicente Friaza   +7 more
doaj   +1 more source

Hematologic dynamics during pregnancy and their association with obstetric complications: a retrospective cohort study

Abstract Objectives Pregnancy alters hematologic state as measured by complete blood counts (CBC), but the longitudinal changes in CBC indices that define healthy pregnancies are not well established.
Veronica Tozzo, Rachel Petherbridge, Kaitlyn James, Sarah Hsu, Chloe Michalopoulos, Brody H. Foy, Tanayott Thaweethai, Christopher Mow, Jacqueline Maya, Carolina Batlle Camero, Lydia Shook, Kathryn J. Gray, Logan Mauney, John M. Higgins, Camille E. Powe   +14 more
openaire   +2 more sources

Clinical and Reproductive Outcomes After Hysteroscopic Repair of Isthmocele

Gynecology Obstetrics & Reproductive Medicine
OBJECTIVE: The growing global prevalence of cesarean delivery has increased the incidence of long-term scar complications, among which isthmocele represents a clinically relevant yet often under-recognized entity.
Inci Oz, Ali Utku Oz
doaj   +1 more source