Results 61 to 70 of about 12,365 (224)

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Hepatic Mechanisms and Therapeutic Target Underpinning Hypercoagulation in Obesity: Insights From Genetic and Transcriptomic Analyses

Exploration, EarlyView.
Obesity‐linked hypercoagulation is driven by fibrinogen overproduction in a specific hepatocyte cluster via IL6 signalling. Genetic and mechanistic studies reveal this pathway as a key target for therapies to mitigate clotting risks and associated complications in obese individuals.
Shumin Li, Gengchen Feng, Xin Huang, Xiao Teng, Ziyi Yang, Yue Liu, Yonghui Jiang, Tao Zhu, Teng Liu, Yunfei Xu, Chang Pan, Han Zhao, Shaozhuang Liu, Shigang Zhao, Zi‐Jiang Chen   +14 more
wiley   +1 more source

Protective Effects of Fenugreek and Stevia Extracts on Dexamethasone‐Induced Testicular Damage in a Rat Model

Food Safety and Health, EarlyView.
Fenugreek and stevia extracts protect against dexamethasone‐induced testicular damage in male rats by enhancing antioxidant defenses, improving sperm quality, and restoring hormonal balance, highlighting their potential as natural therapeutics for preventing corticosteroid‐induced reproductive toxicity.
Mosab Gad, Medhat Ibrahim A. Omar, Mohammed I. Elkhateeb, Ahmed A. Zaky   +3 more
wiley   +1 more source

Geographical Pattern of Testicular Cancer Points to Maternal Exposures Behind Increasing Incidence

International Journal of Cancer, EarlyView.
ABSTRACT Evidence suggests that testicular cancer (TC) originates from germ cell neoplasia in situ arising during fetal development, implying that prenatal environmental exposures may influence disease risk. We investigated whether maternal place of residence during pregnancy is associated with regional variation in TC incidence.
Antti Kaipia, Karri Seppä, Elli Hirvonen, Eetu Mäkinen, Nea Malila, Janne Pitkäniemi, Jorma Toppari, Peter Boström, Heikki Seikkula   +8 more
wiley   +1 more source

Eficácia de intervenção com enoxaparina baseada em sistema de pontuação nos desfechos perinatais de gestantes com trombofilias Usefulness of a scoring system on perinatal outcomes in pregnant women with thrombophilia in the effectiveness of an enoxaparin-based intervention

Revista Brasileira de Ginecologia e Obstetrícia, 2012
OBJETIVO: Avaliar se a intervenção com heparina de baixo peso molecular (HBPM) - enoxaparina sódica - foi eficaz na melhora dos desfechos perinatais de mulheres com trombofillias com base em sistema de pontuação.
Ernesto Antonio Figueiró-Filho, Vanessa Marcon de Oliveira, Ili Breda, Lílian Rezende Coelho, Cristiane Munaretto Ferreira   +4 more
doaj   +1 more source

Sex‐Specific Proteomic Profiling Identifies Pregnancy Zone Protein as a Complement‐Linked Marker of Adverse Prognosis in Esophageal Adenocarcinoma

International Journal of Cancer, EarlyView.
ABSTRACT Esophageal adenocarcinoma (EAC) exhibits marked male predominance with male‐to‐female ratios reaching 8.5:1, yet the molecular basis underlying this sex disparity remains poorly characterized. We analyzed 92 EAC specimens using mass spectrometry–based proteomics, comprising 47 female and 45 male tumors from treatment‐naïve patients ...
Alexander Quaas, Hanna Schiemann, Su Ir Lyu, Thomas Zander, Axel Hillmer, Hans Schlößer, Christiane J. Bruns, Reinhard Büttner, Bastian Grothey   +8 more
wiley   +1 more source

Red cell aplasia and autoimmune hemolytic anemia following immunosuppression with alemtuzumab, mycophenolate, and daclizumab in pancreas transplant recipients

Haematologica, 2007
Background and Objectives Acquired red cell aplasia (RCA) is a rare disorder and can be either idiopathic or associated with certain diseases, pregnancy, or drugs.
Milena Elimelakh, Vanessa Dayton, Katharine S. Park, Angelika C. Gruessner, David Sutherland, Robert B. Howe, Mark T. Reding, Ted Eastlund, Jo-Anne van Burik, Timothy P. Singleton, Rainer W. Gruessner, Nigel S. Key   +11 more
doaj   +1 more source

Postpartum anemia and maternal wellbeing: A cohort analysis of the WOMAN‐2 trial

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective We examined the association between postpartum anemia and maternal wellbeing in women who gave birth with anemia. Methods We conducted a cohort analysis using secondary data from the WOMAN‐2 trial. Between August 2019 and September 2023, women with moderate or severe anemia who were giving birth vaginally were recruited from ...
The WOMAN‐2 Trial Collaborators, Judith Lieber, Katharine Ker, Folasade Adenike Bello, Rizwana Chaudhri, Kiran Javaid, Aasia Kayani, Mwansa Ketty Lubeya, Projestine Muganyizi, Oladapo Olayemi, Bellington Vwalika, Monica Arribas, Eni Balogun, Amy Brenner, Amber Geer, Poppy Mallinson, Raoul Mansukhani, Danielle Prowse, Haleema Shakur‐Still, Ian Roberts, France Donnay, Racheal Phiri, Tina Lavender, Ghazala Mahmud, Haleema Shakur‐Still, Ian Roberts, Jens Kieckbusch, James Lawrence, Sari Watson, Jane Armitage, Maria Quigley, Olufemi T. Oladapo, Sabaratnam Arulkumaran, Imelda Bates, Rizwana Chaudhri, Bukola Fawole, Katharine Ker, Ian Roberts, Haleema Shakur‐Still, Eni Balogun, Danielle Prowse, Danielle Beaumont, Charlotte Fleming, Monica Arribas, Collette Barrow, Llion Roberts, Amber Geer, Julio Gil Onandia, Madeleine Cargill, Andrew Thayne, Christiana Alao, Petula Buck, Raoul Mansukhani, Tim Collier, Katharine Ker, Mbwana Mohammed, Amy Brenner, Myriam Benyahia, Judith Lieber, Haleema Shakur‐Still, Ian Roberts, Rizwana Chaudhri, Aasia Kayani, Kiran Javaid, Projestine Muganyizi, Alice Kawala, Rose Temba, Oladapo Olayemi, Folasade Adenike Bello, Olujide Okunade, Bellington Vwalika, Aziz‐un‐Nisa Abbasi, Ruqqia Sultana, Shehla Noor, Ansa Islam, Sadia Bibi, Sundus Khan, Wajeeha Khurshid, Shahida Magsi, Basma Zia, Haleema Yasmin, Khadija Bano, Saba Khan, Naheed Fatima, Bushra Sher Zaman, Sohail Mahmood Chaudhry, Shakila Yasmin, Khiaynat Sarwar Hashmi, Nadia Babar, Arif Tajammul, Alia Bashir, Farah Siddique, Fouzia Perveen, Nusrat Shah Kamal, Riffat Jaleel, Sarah Kazi, Aruna Hira, Pushpa Makhija, Syeda Batool Mazhar, Nasira Tasnim, Saera Afghan, Mussarat Batool, Sobia Luqman, Fouzia Kashif, Shaista Hifaz Abro, Javeria Abro, Najma Ghaffar, Rakhshanda Mushtaq, Safia Bibi, Shamsa Humayun, Zohra Khanum, Noreen Akmal, Shamila Ijaz Munir, Aisha Malik, Amna Zia Eusaph, Sofia Manzoor, Khola Yousaf, Misbah Kausar, Yasmeen Waqas, Naila Ehsan, Aisha Siddiqa, Uzma Suhail Afridi, Nosheen Sikandar, Rehana Kamaal, Mehnaz Khakwani, Rashida Perveen, Huma Quddusi, Hajira Masood, Syeda Ali, Asma Akhter, Mubashra Samina, Sana Ishfaque, Rizwana Chaudhri, Humaira Bilqis, Shahid Irshad Rao, Saima Ashraf, Uzma Shaheen, Tayyiba Wasim, Natasha Rasool, Nabeela Waheed, Khansa Iqbal, Shahida Husain Tarar, Rizwana Khalid, Rubina Sohail, Shehla Kanwal, Shagufta Saeed Sial, Humera Noreen, Naila Israr, Shehla Baqai, Asifa Siraj, Luzango Maembe, Julius Nyambarino, Enid Simon Chiwanga, Lazaro Y. Madeha, Francis Ngimwichi Joseph, Evelyne Ludovick, Baya H. Kissiwa, Sangalala Mtingele, Vincent Tarimo, Alfred Secha, Hudson August Manyanga, Idrisa Hussein, Alphonce Moyo, Delila Msigwa, France John Rwegoshora, Delfina Mkenda, Mojisola Mobolaji‐Ojibara, Michael Babalola, Owa Olorunfemi Oludele, Samuel Ojo, Oladipo Aremu, Kehinde Ogundairo, Oyewole Tunde Aremu, Gazaal Rasheedat, Iman Usman, Auwal Shuaibu, Adewale Adeyemi, Olufemi Aworinde, Theresa Irinyenikan, Mwansa Ketty Lubeya, Kenneth Chanda   +180 more
wiley   +1 more source

Management Challenges of Acute Promyelocytic Leukemia in Pregnancy: A Case Report

Journal of Investigative Medicine High Impact Case Reports
Acute promyelocytic leukemia (APML) is a rare hematologic emergency with a high mortality rate due to bleeding diathesis, which is due to a disseminated intravascular coagulation-like coagulopathy; APML is complicated enough to treat on its own and ...
Joseph Hemry BS, Pranati Shah DO, Iris Lee MD, Aren Dermarderosian BS, Mojtaba Akhtari MD   +4 more
doaj   +1 more source

Association between red blood cell distribution width coefficient of variation and post-treatment bilirubin decline velocity in neonatal hyperbilirubinemia

Frontiers in Pediatrics
BackgroundRed blood cell distribution width coefficient of variation (RDW-CV) reflects erythrocyte heterogeneity, but its correlation with posttreatment bilirubin kinetics in neonatal hyperbilirubinemia (NHB) remains underexplored.MethodsThis cross ...
Hongjuan Wei, Tingting Zhang, Rufeng Ji, Yinyan Tang   +3 more
doaj   +1 more source