Results 151 to 160 of about 117,944 (273)

Immune dysregulation as a key driver of peripartum cardiomyopathy – an exploratory advanced imaging and biomarker study

European Journal of Heart Failure, EarlyView.
Physiological postpartum remodelling and the pathological processes involved in peripartum cardiomyopathy (PPCM). 18FDG‐PET‐CT, 18F‐fluorodeoxyglucose positron emission tomography‐computed tomography; CCL3, chemokine (C‐C motif) ligand 3; CMR, cardiovascular magnetic resonance; CRP, C‐reactive protein; CSF‐1, colony‐stimulating factor 1; CXCL10 ...
Julian Hoevelmann, Charle Viljoen, Tessa Kotze, Carlos Libhaber, Stephen Jermy, Morné Kahts, Fareda Jakoet‐Bassier, Petronella Samuels, Olivia Briton, Lynette Cilliers, Denise Hilfiker‐Kleiner, Peter van der Meer, Michael Böhm, Ntobeko A.B. Ntusi, Karen Sliwa   +14 more
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Influenza Vaccination Coverage among Pregnant Women in Rhode Island: The Importance of the Prenatal Care Provider Role [PDF]

, 2005
Rhode Island's data from the Pregnancy Risk Assessment Monitoring System (PRAMS) demonstrate that health care providers play a critical role in the acceptance of influenza vaccine by pregnant ...

core  

Status non‐epilepticus

Epileptic Disorders, EarlyView.
Abstract Objective Status non‐epilepticus is characterized by recurrent or prolonged psychogenic non‐epileptic seizures (PNES), which are often mistaken for status epilepticus (SE). This study focuses on the misdiagnosis of convulsive SE in patients whose seizures were of psychogenic origin.
Ronen Spierer, Moshe Herskovitz
wiley   +1 more source

Gestantes con antígeno de superficie positivo: resultado de su pesquisaje en 5 837 casos

Revista Cubana de Higiene y Epidemiología
Se realiza un estudio observacional, analítico, con un modelo de diseño del tipo casos y controles; en un total de 5 837 gestantes, pesquisadas en los municipios Guanabacoa y Regla desde el 1 de junio de 1990 hasta el 1 de junio de 1994. Se detectaron 20
Rodolfo Fernández Milián, Gil Vicente Sarmiento Brooks, Luis Fernández Machín, Carmen Córdova Medina   +3 more
doaj  

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Deciphering of nutritional profile, therapeutic potential, and networking of bioactive compounds of Moringa oleifera: A comprehensive review

Food Biomacromolecules, EarlyView.
The graphical abstract signifies the nutritional profile of various parts of the Moringa oleifera plant, including dried leaves, fresh leaves, leaf powder, seeds, and pods; along with it’s bioactive substance and protein profiling of aqueous concentrates derived from the fruit, seed, and leaf.
Rajesh Kumar, Sunita Khatak, Vandana, Adarsh Kumar Shukla, Surbhi Panwar, Ashwani Kumar   +5 more
wiley   +1 more source

The Piggy Solution: Harnessing Food Waste for Sustainable Hog Farming

Global Challenges, EarlyView.
This review explores the use of food waste as a sustainable feed alternative for hog farming. By repurposing food waste, the approach reduces landfill waste, lowers feed costs, and mitigates environmental impacts like greenhouse gas emissions. The study discusses nutritional adequacy, safety regulations, processing methods, and business models ...
Matthew C. Ogwu, Catherine E. Hills, Silvana Pietrosemoli   +2 more
wiley   +1 more source

The Impact of Child Disability on Parental Outcomes: Evidence From Sweden

Health Economics, EarlyView.
ABSTRACT Parents of children with disabilities may face higher labor‐market penalties given the extra care and support required. Using Swedish administrative data, we focus on first‐born children with Cerebral Palsy (CP) to estimate impacts on parental labor‐market outcomes.
Derek Asuman, Ulf‐G. Gerdtham, Ann I. Alriksson‐Schmidt, Martin Nordin, Johan Jarl   +4 more
wiley   +1 more source