Results 41 to 50 of about 572,077 (339)
Obstetric and long-term kidney outcomes in renal transplant recipients: a 40 year single-centre study [PDF]
, 2016 Female renal transplant recipients of childbearing age may ask what the outcomes are for pregnancy and whether pregnancy will affect graft function. We analyzed obstetric and transplant outcomes among renal transplant recipients in our center who have ...
Brennand, Janet E. +6 more
core +1 more source
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
Anorexia nervosa and reproduction: connecting brain to gonads [PDF]
, 2020 Anorexia nervosa (AN) is a psychiatric disorder that predominantly affects young women and is characterized by low caloric intake and a major dissatisfaction with one’s body image.
Ciobanu, Corina +3 more
core +2 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
UTERINE MALFORMATIONS AND PREGNANCY COMPLICATIONS
Arta Medica, 2020 Summary The incidence of congenital uterine malformations is 3-5%. Often they lead to reproductive loss and other complications of pregnancy. The correct and timely diagnosis and surgical correction of abnormalities of the Müllerian duct is one of the
Nadejda Codreanu, Daniela Andries
doaj
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Management of psoriasis in pregnancy – a review of the evidence to date
Drugs in Context, 2020 The onset of psoriasis collides with women’s reproductive timeframe, and pregnancy brings challenges to its treatment. Indeed, the health of both mother and foetus must be considered.
Clara Ferreira +3 more
doaj +1 more source
Characteristics Overview of Mother with Perinatal Death at Dr. Soetomo Hospital in 2015 [PDF]
, 2016 Objectives: to determine the frequency distribution of perinatal mortality and maternal characteristic features in terms of age, parity, gestational age and pregnancy complications in Dr.Soetomo Hospital Surabaya in 2015.
Haslinda, Y. (Yulisa) +1 more
core
Understanding infant feeding choice from the Great Depression to the baby boom in the U.S. [PDF]
, 2018 Objectives: The objectives of this study were to describe the rates of and factors associated with exclusive breastfeeding (XBR), exclusive breast feeding + breast and bottle-feeding (Ever BR), and of exclusive bottle-feeding (XBOT) from 1925-1964 among ...
Pilles, Kiona Natasha
core +1 more source