Results 71 to 80 of about 156,635 (305)

Association between plasma fluoride levels and pregnancy complications in women living in the rural and urban areas of Settat-Morocco

Gülhane Tıp Dergisi, 2023
Aims:This study aimed to investigate the relationship between plasma fluoride levels and pregnancy complications among rural and urban women living in the Settat province of Morocco, where fluorosis is endemic.Methods:This cross-sectional study included ...
Lalla Asmaa Katir Masnaoui, Fatine Hadrya, Abdellatif Rahim, Bouchra El Amiri, Boubker Nasser, Abdelkhalid Essamadi   +5 more
doaj   +1 more source

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

Advanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim, Ha Kyeong Lee, Zulfikar Azam, Jeong Uk Choi, Riajul Wahab, Na Kyeong Lee, Yoon Gun Ko, So‐Young Choi, Se‐Ra Lee, Wan Seob Shim, Taeeung Kim, In‐San Kim, Farzana Alam, Sang Yoon Kim, Seong Who Kim, Youngro Byun, Taslim A Al‐Hilal   +16 more
wiley   +1 more source

Pregnancy-Induced Hypertension: Current Concepts [PDF]

Anaesthesia and Intensive Care, 1989
This brief review outlines current concepts concerning the aetiology and pathophysiology of pregnancy-induced hypertension and, based upon these concepts, presents a plan of intensive care management for the severe forms of this condition.
openaire   +2 more sources

Observations related to chronologic and gynecologic age in pregnant adolescents. [PDF]

, 1984
A low chronologic age (less than or equal to 15 years) and low gynecologic age (less than or equal to 2 years) have been considered factors that increase medical complications among adolescent pregnant women. Gynecologic age (GA) is defined in this study
Felice, ME, Hollingsworth, DR, James, M, Shragg, P   +3 more
core  

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Ocular manifestation of pregnancy-induced hypertension

MGM Journal of Medical Sciences, 2021
Background and Objectives: Pregnancy-induced hypertension (PIH) is a challenging obstetric condition that can result in grave complications. The retina is a unique site where the vasculature in the human body is visualized directly with the help of an ...
Sheetal Devaru, Kalpana Badami Nagaraj, Snehal Himmatlal Shah   +2 more
doaj   +1 more source

A Practical Understanding of Preeclampsia for a Nurse in a Third World Setting [PDF]

, 2019
Preeclampsia is a disease of pregnancy that affects approximately 3-5% of women with child. It is one of the primary causes of mortality in mothers and babies across the globe. The exact cause, pathogenesis, or disease progression is unknown.
Lovin, Anna
core   +1 more source

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

Effects of auriculotherapy on gestational hypertension: Randomized controlled trial study

Iranian Journal of Nursing and Midwifery Research
Background: This study aims to observe how auriculotherapy acts as a nonpharmacological treatment for pregnant women's gestational hypertension. Materials and Methods: This study was a randomized controlled trial.
Ladan Keshtkar, Fatemeh Ranjkesh, Mohammad Habibi, Farnoosh Rashvand   +3 more
doaj   +1 more source