Results 141 to 150 of about 3,433,369 (265)

Men, sexuality and crisis pregnancy: A study of men’s experiences

, 2007
This research report was commissioned by the Crisis Pregnancy Agency with the overall aim of increasing understanding of men, sexuality and crisis pregnancy.
Hogan, Fergus, Ferguson, Harry
core  

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

Improving knowledge regarding abortions performed on Irish women in the UK

, 2007
The overall aim of this study was to provide detailed statistics on women who travel from Ireland1 to Great Britain for an abortion. This was done by using data on abortion notifications held by the Department of Health in London, plus data available ...
Clements, Steve, Ingham, Roger
core  

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Crisis Pregnancy Agency statistical report 2005: Fertility and crisis pregnancy indices

, 2005
This report aims to present, in one document, a range of statistical indices that shed light on reproductive decision making and childbearing in Ireland.
McGrath, Deirdre, Smith, Mary, O’Keeffe, Stephanie   +2 more
core  

Developmental origins of pregnancy loss in cattle. [PDF]

Anim Reprod
Flores-Borobia I, Pérez-Gómez A, Martínez de Los Reyes N, González-Brusi L, Galiano-Cogolludo B, Irala C, Siegmund-Sabater A, Ramos-Ibeas P, Bermejo-Álvarez P.   +8 more
europepmc   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Advanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou, Shu Ding, Zhenyi Zhang, Qiaoling Shangguan, Jie Qiao, Peijie Zhou, Yidong Chen   +6 more
wiley   +1 more source

A review of the international literature on the role of outside facilitators in the delivery of school-based sex education

, 2009
Schools are one of the main sites where knowledge can be imparted on sexuality and relationships. There is widespread parental support in the Irish context for the provision of school-based sex education (Morgan, 2000; North Western Health Board, 2004;
Doyle, Louise, Mayock, Paula, Sheaf, Greg, Sherlock, Leslie, Andrews, Lorraine, de Vries, Jan, Higgins, Agnes   +6 more
core  

IFN-γ+ NK cells as a potential predictor of pregnancy loss in unexplained recurrent pregnancy loss. [PDF]

Int J Med Sci
Yan N, Lee P, Jie H, Long L, Fu Y, Zhou C, Yuan Y.   +6 more
europepmc   +1 more source

Phase Separation, Material State, and Condensate Fate in Mammalian Autophagy

Advanced Science, EarlyView.
ABSTRACT Biomolecular phase separation has emerged as a key organizing principle in macroautophagy (hereafter autophagy). In mammalian cells, phase‐separated condensates not only serve as substrates for selective degradation, but also act as dynamic platforms for cargo recognition, signaling integration, and autophagosome assembly.
Yuanqiang Lin, Mingran Dai, Enyong Dai, Rui Kang, Daniel J. Klionsky, Daolin Tang, Yu Sun, Ningning Lv, Junnan Jiang   +8 more
wiley   +1 more source