Results 241 to 250 of about 823,485 (329)

Pregnancy Outcome [PDF]

BJOG: An International Journal of Obstetrics & Gynaecology, 2019
openaire   +3 more sources

Maternal gut microbiota influences immune activation at the maternal-fetal interface affecting pregnancy outcome. [PDF]

Nat Commun
Giugliano S, Gatti A, Rusin M, Schorn T, Pimazzoni S, Calanni-Pileri M, Fraccascia V, Carloni S, Rescigno M.   +8 more
europepmc   +1 more source

Impact of Enoxaparin on Maternal and Fetal Outcomes in In Vitro Fertilization (IVF) Pregnancies With Thyroid Autoimmunity: A Real-World, Single-Center, Retrospective, Observational Study [PDF]

G. A. Rama Raju, Ponnada Sravani, Pranati Mahapatro, Aruna Kovvuri, Vishal Dave, Vivek Sharma, Deepak Bunger   +6 more
openalex   +1 more source

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

Advanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu, Yunyuan Yu, Guangrong Yin, Huiqun Hu, Shishuo Li, Yuting Tang, Yimin Liu, Maoyuan Li, Liang liang Wang, Chao Xu, Gongyin Zhao, Baojun Zhou, Yuji Wang   +12 more
wiley   +1 more source

Heterotopic Pregnancy Following Ovulation Induction With Successful Pregnancy Outcome: A Case Report. [PDF]

Clin Case Rep
Ghimire U, Manandhar I, Shrestha S, Sah R, Lamichhane J, Gautam J.   +5 more
europepmc   +1 more source

Maternal, perinatal, neonatal, and postpartum outcomes following SARS-CoV-2 infection in pregnancy: A WHO multi-country prospective cohort study  [PDF]

WHO COVID-19 & Pregnancy Cohort Study Group, Edna Kara, Sami L Gottlieb, Nathalie J Broutet, Anna Thorson, Marie Delnord, Ibukun-Oluwa Omolade Abejirinde, Ronaldo Silva, Soe Soe Thwin, Daniel Giordano, Ndema A Habib, Edgardo Abalos, José G Cecatti, Maria L. Costa, Renato T. Souza, Seni Kouanda, Desiré L Dahourou, Henri Gautier Ouedraogo, Sergio Muñoz, Gerardo Espinoza, Araceli Saavedra, Kwasi Torpey, Chris Guure, Ernest Maya, Emefa Modey, Marleen Temmerman, Rodney D. Adam, Ingrid Gichere, Sura Mandeep, Sarah Saleem, Najia Ghanchi, Saleem Jessani, Erlidia Llamas-Clark, Emmanuel S. Baja, Mayan U Lumandas, Alejandro Orrico‐Sánchez, Antonio Carmona, Henda Triki, Mariem Gdoura   +38 more
openalex   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Association between clinical subtypes and pregnancy outcome of cervical incompetence: a retrospective cohort study. [PDF]

BMC Pregnancy Childbirth
Xiao H, Xing X, Zhang C, Shao Y.
europepmc   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

A Microbiota‐ and IL‐15‐Dependent Innate‐Like B Cell Progenitor Expressing E4BP4

Advanced Science, EarlyView.
This work identifies CD3.NKp46.CD19.NK1.1. NK‐B cells enriched in PDK1‐deficient yet present in wild‐type bone marrow. IL‐15 (via CD122) and TLR9‐microbiota signaling maintain their E4BP4 expression. These cells demonstrate innate immunity, preferentially differentiate into B cells, and unveil a novel microbiota‐ and IL‐15‐dependent regulatory pathway ...
Junming He, Xinlei Hou, Xiaomei Feng, Yayun Dong, Mengqi Ren, Surong Deng, Xinru Yang, Donglin Chen, Lingna Zhao, Shasha Chen, Meixiang Yang, Zhongjun Dong   +11 more
wiley   +1 more source