Results 251 to 260 of about 836,602 (329)

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

open access: yesAdvanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu   +9 more
wiley   +1 more source

Heterogeneity of Gestational Diabetes and Risk for Adverse Pregnancy Outcome: A Cohort Study.

open access: yesJ Clin Endocrinol Metab
Gong Y   +13 more
europepmc   +1 more source

Principles for Rigorous Design and Application of Synthetic Microbial Communities

open access: yesAdvanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang   +21 more
wiley   +1 more source

PFOS Disrupts Oocyte Maturation and Early Embryonic Development via Ovarian FOXK1 O‐GlcNAcylation in Mice

open access: yesAdvanced Science, EarlyView.
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han   +16 more
wiley   +1 more source

Maternal gut microbiota influences immune activation at the maternal-fetal interface affecting pregnancy outcome. [PDF]

open access: yesNat Commun
Giugliano S   +8 more
europepmc   +1 more source

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