Results 71 to 80 of about 9,804,588 (356)

Maternal and neonatal outcomes in pregnant women with severe thrombocytopenia: insights from a retrospective 8-year cohort study in China

Research and Practice in Thrombosis and Haemostasis
Background: Severe thrombocytopenia during pregnancy is uncommon but poses substantial challenges for obstetric management because of potential maternal bleeding and adverse neonatal outcomes.
Kangjia Chen, Qiao Liu, Jiawei Tang, Hui Chen, Xinghui Wen, Dunjin Chen, Shuguang Zhou, Fang He   +7 more
doaj   +1 more source

Association between adverse pregnancy outcome and imbalance in angiogenic regulators and oxidative stress biomarkers in gestational hypertension and preeclampsia

BMC Pregnancy and Childbirth, 2015
BackgroundGestational hypertension (GH) and Preeclampsia, (PE) are the most complicated amongst hypertensive disorders of pregnancy. The mechanism that links hypertension in pregnancy to adverse maternal outcomes is not fully understood though some ...
C. Turpin, S. Sakyi, W. Owiredu, Richard K. D. Ephraim, E. Anto   +4 more
semanticscholar   +1 more source

Pregnancy and neonatal outcomes of COVID‐19: coreporting of common outcomes from PAN‐COVID and AAP‐SONPM registries

Ultrasound in Obstetrics and Gynecology, 2021
Few large cohort studies have reported data on maternal, fetal, perinatal and neonatal outcomes associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection in pregnancy.
E. Mullins, M. Hudak, J. Banerjee, T. Getzlaff, J. Townson, K. Barnette, R. Playle, A. Perry, T. Bourne, C. Lees   +9 more
semanticscholar   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

The Hyperglycemia and Adverse Pregnancy Outcome Study

Diabetes Care, 2012
OBJECTIVE To determine associations of gestational diabetes mellitus (GDM) and obesity with adverse pregnancy outcomes in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study. RESEARCH DESIGN AND METHODS Participants underwent a 75-g oral glucose
P. Catalano, H. Mcintyre, J. Cruickshank, D. McCance, A. Dyer, B. Metzger, L. P. Lowe, E. Trimble, D. Coustan, D. Hadden, B. Persson, M. Hod, J. Oats   +12 more
semanticscholar   +1 more source

Immune system function, stress, exercise and nutrition profile can affect pregnancy outcome: Lessons from a Mediterranean cohort [PDF]

, 2013
This article is made available through the Brunel Open Access Publishing Fund.Pregnancy is associated with major physiological and future psychosocial changes, and maternal adaptation to these changes is crucial for normal foetal development ...
Karteris, E, Zachariades, E, Goumenou, A, Gidron, Y, Pados, G, Mparmpakas, D   +5 more
core   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Outcome of Pregnancy in Lupus

Bangabandhu Sheikh Mujib Medical University Journal, 2012
Background: Pregnancy in patients with SLE is associated with a high risk of maternal disease exacerbation in active disease state and adverse fetal outcome.
Syeda Sayeeda, Firoza Begum, Nahreen Akhtar, Farzana Sharmin   +3 more
doaj   +1 more source

The cessation in pregnancy incentives trial (CPIT): study protocol for a randomized controlled trial [PDF]

, 2012
Background: Seventy percent of women in Scotland have at least one baby, making pregnancy an opportunity to help most young women quit smoking before their own health is irreparably compromised.
De Caestecker, L., Boyd Kathleen, Liz Grant, Bauld Linda, Tappin, David, Sinclair, Lesley, Grant, Liz, Friel, Brenda, Radley, Andrew, Linda de Caestecker, Radley, Andrew; id_orcid, MacAskill Susan, Tannahill, Carol, Cameron, Alan, Carol Tannahill, Coleman, T., Susan MacAskill, Boyd, K., Coleman Tim, Coleman, Tim, McConnachie, A., Sinclair Lesley, Cameron Alan, Radley, A., Briggs, Andrew, McConnachie, Alex, Tappin David M, Briggs Andrew, Tim Coleman, Tannahill Carol, Radley Andrew, Macaskill, S., Lesley Sinclair, Tannahill, C., Kathleen Boyd, Andrew Briggs, Cameron, A., MacAskill, Susan, Friel, B., David M Tappin, Bauld, L., Tappin, D.M., McConnachie Alex, Alex McConnachie, de Caestecker Linda, Briggs, A., Bauld, Linda, de Caestecker, Linda, Sinclair, L., Boyd, Kathleen, Friel Brenda, Andrew Radley, Tappin, David M., Linda Bauld, Brenda Friel, Grant, L., Grant Liz, Alan Cameron   +57 more
core   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source