Results 211 to 220 of about 6,457,257 (341)

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Pregnancy Outcomes in Women With Rheumatic Mitral Valve Disease: Results From the Registry of Pregnancy and Cardiac Disease

Circulation, 2018
I. V. van Hagen, S. Thorne, N. Taha, G. Youssef, A. Elnagar, H. Gabriel, Y. Elrakshy, B. Iung, Mark R. Johnson, R. Hall, J. Roos‐Hesselink   +10 more
semanticscholar   +1 more source

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

Advanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu, Yunyuan Yu, Guangrong Yin, Huiqun Hu, Shishuo Li, Yuting Tang, Yimin Liu, Maoyuan Li, Liang liang Wang, Chao Xu, Gongyin Zhao, Baojun Zhou, Yuji Wang   +12 more
wiley   +1 more source

Maternal Betahistine Exposure and Pregnancy Outcomes: A Retrospective Cohort Study. [PDF]

Cureus
Alsaad D, Ahmed A, Elkassem W, Moursi A, Minisha F.   +4 more
europepmc   +1 more source

Short interpregnancy interval can lead to adverse pregnancy outcomes: A meta-analysis

, 2022
Yumei Wang, Can Zeng, Yuhong Chen, Liu Yang, Di Tian, Xinghui Liu, Yonghong Lin   +6 more
openalex   +1 more source

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

Carbon monoxide levels, smoking and adverse pregnancy outcomes. [PDF]

Acta Obstet Gynecol Scand
Galka K, Shea M, Aye CYL, Impey L.
europepmc   +1 more source

Effect of repeated vitrification of human embryos on pregnancy and neonatal outcomes [PDF]

Yan Huang, Yi Cheng, Min Zhang, Yiqing Chen, Rong Zhou, Dewei Lin, Xinyu Guo   +6 more
openalex   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

IVF and pregnancy outcomes: the triumphs, challenges, and unanswered questions. [PDF]

J Ovarian Res
Bentov Y, Schenker J.
europepmc   +1 more source