Results 161 to 170 of about 1,077,944 (364)
NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction
Advanced Science, EarlyView.NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu +15 more
wiley +1 more source
833: The effect of preventive antibiotic treatment in the postpartum period on urinary tract infection (UTI) rate in women treated during pregnancy for recurrent UTI – a prospective randomized controlled study [PDF]
, 2014 Zohar Nachum +4 more
openalex +1 more source
Advanced Science, EarlyView.The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang +10 more
wiley +1 more source
Advanced Science, EarlyView.TGFβ2 signaling‐mediated migration/invasion and migrasome formation are suppressed in recurrent miscarriage (RM) versus healthy control villous tissues and are negatively associated with unexplained RM. In mechanism, TGFβ2 promotes trophoblast cell migration/invasion and migrasome formation, all of which are suppressed by lnc‐HZ05. In details, lnc‐HZ05
Weina Chen +14 more
wiley +1 more source
Advanced Science, EarlyView.The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu +17 more
wiley +1 more source
Advanced Science, EarlyView.Within the hepatitis E virus (HEV) ORF1 polyprotein, the X domain interacts with viral RNA‐dependent RNA polymerase (RdRp), forming a functional “pocket‐like” cavity (PC) that is crucial for viral replication. Structure‐based screening, surface plasmon resonance (SPR) assays, and HEV model validation collectively identify saikosaponin D and ...
Xiaohui Ding +15 more
wiley +1 more source
Body Mass Index and success rate of IVF
Journal of Family and Reproductive Health, 2007 Objective: This study investigated the effect of body mass index (BMI) on the success rate of IVF for couples with different causes of infertility. Materials and methods: In a cross sectional descriptive- analytic study conducted simultaneously in Mehr ...
Farshad Savadkouhi +2 more
doaj
Preconception nutrition knowledge, dietary intakes and lifestyle characteristics of Auckland women : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Science in Nutritional Science at Massey University [PDF]
, 2006 Introduction Adequate nutritional status prior to conception and during early pregnancy is important in achieving a healthy pregnancy outcome. This study examined preconception nutrition knowledge, and dietary and lifestyle habits in Auckland women of ...
Proctor, Janie
core
Advanced Science, EarlyView.A human subventricular zone‐on‐a‐chip is developed to model intraventricular hemorrhage (IVH) in preterm infants. This platform enables the study of inflammation‐driven neurogenic disruption. Exposure to hemorrhagic cerebrospinal fluid and red blood cell lysate activated inflammatory pathways, with IL1B emerging as a key mediator.
Laura Nicoleti Zamproni +6 more
wiley +1 more source