Results 141 to 150 of about 539,337 (267)

Impact of ovarian stimulation duration in GnRH antagonist protocols on the cumulative ongoing pregnancy rate in women with normal ovarian reserve: a cohort study. [PDF]

Reprod Biol Endocrinol
Cohen Aloro L, Saïs E, Becquart C, Thomas H, Souare F, Sellami I, Mayeur A, Hesters L, Grynberg M, Sonigo C.   +9 more
europepmc   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

Advanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao, Ziqi Zhang, Anqi Chen, Yanbo Liu, Yuling Lin, Lina Yu, Ruixin Shi, Aolei Guo, Yan Mao, Ganggui Lou, Chaojun Li, Luhong Wen, Guijun Yan, Haixiang Sun   +13 more
wiley   +1 more source

Changes in the comprehensive unassisted pregnancy rate as a possible marker of declining human fecundity. [PDF]

Sci Rep
Lindahl-Jacobsen R, Beck AL, Priskorn L, Holmboe SA, Andersson AM, Juul A, Skakkebaek NE.   +6 more
europepmc   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Comparison of Pregnancy Rate and Live Birth Rate of Intracytoplasmic Sperm Injection Cycles Using Fresh Versus Frozen-Thawed Testicular Sperm. [PDF]

Obstet Gynecol Int
Abualiat ZM, Makki JS, Aljebeli SM, Bamousa RO, Alamri OZ, Alabdullah AF, Al Fozan H.   +6 more
europepmc   +1 more source

MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis

Advanced Science, EarlyView.
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li, Chun‐Hui Zhang, Yong Wang, Cheng‐Yuan Li, Da‐Rong Wen, Xi Xia, Liang Zhou, Wei‐Ping Qian, Qing‐Yuan Sun, Chang‐Zhong Li   +9 more
wiley   +1 more source

Effect of acupuncture pretreatment on clinical pregnancy rate in women with diminished ovarian reserve undergoing IVF-ET: study protocol for a multicenter randomized controlled trial. [PDF]

Front Endocrinol (Lausanne)
Liu X, Su C, Li J, Chen L, Zhang Q, Sun Y, Xu J, Zhang C, Cheng X, Li X, Yang H, Xie Y, Yang J, Zhu N, Lu W, Su T, Shang W, Lu Q, Yang L, Li J, Hang T, Qi L, Xiao Q, Li W, Gao F, Wang X, Du P, An D, Xu H, Fang Y.   +29 more
europepmc   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

Effect of health education on mood and pregnancy rate among infertile patients undergoing assisted reproduction: A systematic review and meta-analysis. [PDF]

Medicine (Baltimore)
Xie R, Xie F.
europepmc   +1 more source

Pregnancy rate, maternal and neonatal outcomes among breast cancer survivors: A systematic review. [PDF]

Nurs Open, 2023
Azizi M, Ebrahimi E, Moghadam ZB, Shahhosseini Z, Modarres M.   +4 more
europepmc   +1 more source