This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang +15 more
wiley +1 more source
Endometrial Thickness Change in Response to Progesterone is Associated with Ongoing Pregnancy Rate in Women with Treated Intrauterine Adhesion - A Prospective Cohort Study. [PDF]
Hou Z +7 more
europepmc +1 more source
Effects of GLP1RAs on pregnancy rate and menstrual cyclicity in women with polycystic ovary syndrome: a meta-analysis and systematic review. [PDF]
Zhou L, Qu H, Yang L, Shou L.
europepmc +1 more source
CircPROSC promotes craniosynostosis by sponging miR‐6815‐5p, thereby activating WNT3A/β‐catenin signaling and enhancing RUNX2‐mediated osteogenesis. Targeted silencing of circPROSC with MSC membrane–coated siRNA nanoparticles (MM@Lipo/si‐circPROSC) delivered postnatally into cranial sutures attenuates premature suture closure in Twist1+/– mice ...
Zhenkun Weng +6 more
wiley +1 more source
Large-Scale Embryo Transfer Operation in Dromedary Camels: Retrospective Analysis of the Association Between Key Clinical Factors and the 2-Month Pregnancy Rate. [PDF]
Osman TK, Ismail ST, El-Sherbiny HR.
europepmc +1 more source
Increased Serum Levels of Phoenixin-14, Nesfatin-1 and Dopamine Are Associated with Positive Pregnancy Rate after Ovarian Stimulation. [PDF]
Piróg M +3 more
europepmc +1 more source
Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama +17 more
wiley +1 more source
Analysis of influencing factors of clinical pregnancy rate in second cycle intrauterine insemination. [PDF]
Li L, Wang M, Wang H, Yong M, Wang W.
europepmc +1 more source

