Dosing Interval Extension of Dupilumab in CRSwNP: Five‐Year Real World Outcomes
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent, often Type 2‐mediated inflammatory disease that markedly impairs quality of life. While dupilumab provides rapid improvement, there is limited evidence on long‐term outcomes beyond 2 years, and the clinical impact of dosing‐interval extension remains unclear.
Nicholas J. Campion +15 more
wiley +1 more source
Imbalance of naive and memory T lymphocytes with sustained high cellular activation during the first year of life from uninfected children born to HIV-1-infected mothers on HAART [PDF]
, 2008 The immune consequences of in utero HIV exposure to uninfected children whose mothers were submitted to highly active antiretroviral therapy (HAART) during gestation are not well defined.
Angelis, Daniela Sousa Araujo de +7 more
core +2 more sources
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda +4 more
wiley +1 more source
Learning from Teen Childbearing Experiences of Close Friends: Evidence Using Miscarriages as a Natural Experiment [PDF]
, 2013 We examine peer effects in teen childbearing among close friends, using miscarriages as a natural experiment. We use 775 women from the core sample of Add Health who had a friend with a teen pregnancy.
Fletcher, Jason, Yakusheva, Olga
core +1 more source
Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases
Animal Models and Experimental Medicine, EarlyView.Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam +4 more
wiley +1 more source
Coccidioidomycosis Complement Fixation Titer Trends in the Age of Antifungals. [PDF]
, 2018 Coccidioidomycosis is associated with a broad spectrum of illness severity, ranging from asymptomatic or self-limited pulmonary infection to life-threatening manifestations of disseminated disease.
Bays, Derek +6 more
core
Somatic Mutations in Acquired Pure Red Cell Aplasia: Incidence and Implications
American Journal of Hematology, EarlyView.
Robert T. Means Jr
wiley +1 more source
A microscopically assisted limited colectomy mouse model of early colon cancer
Animal Models and Experimental Medicine, EarlyView.Establishment, surgery, and evaluation process of a microscope‐assisted limited colon resection mouse model for early‐stage colon cancer. Abstract Background Currently, there is a lack of an adequate rodent model for investigating surgical techniques and comprehensive treatment options for patients with colorectal cancer (CRC).
Yu Han +3 more
wiley +1 more source
Study of the possibility of immunological rejection of embryos as a cause of reproductive failure [PDF]
, 1969 Call number: LD2668 .T4 1969 M44Master of ...
Merker, Jerry W.
core