Results 51 to 60 of about 370,474 (302)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

“Hypothyroidism screening during first trimester of pregnancy”

open access: yesBMC Pregnancy and Childbirth, 2017
Background Subclinical hypothyroidism is defined as an elevated thyroid-stimulating hormone level with a normal thyroxin level without signs or symptoms of hypothyroidism. Although it is well accepted that overt hypothyroidism has a deleterious impact on
María Castillo Lara   +8 more
doaj   +1 more source

Prenatal Diagnosis and Pregnancy Termination in Jewish and Muslim Women with a Deaf Child in Israel

open access: yesChildren, 2023
Deafness is the most common sensory disability in humans, influencing all aspects of life, However, early diagnosis of hearing impairment and initiating the rehabilitation process are of great importance to enable the development of language and ...
Aliza Amiel   +2 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Comparison of bovine pregnancy associated glycoproteins (bpag- serum and milk), bovine pregnancy specific protein b (bpsp-b) tests with each other and with transrectal ultrasonographic findings for early pregnancy diagnosis [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2018
The aim of this study was to compare the accuracy of bovine pregnancy-associated glycoproteins (bPAG) and bovine pregnancy-specific protein B (bPSP-B) tests with transrectal ultrasonography (TRUS) for early pregnancy diagnosis in dairy cows.
Osman ERGENE   +3 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Changes in biochemical tests in pregnancy and their clinical significance

open access: yes, 2018
Interpretation of laboratory investigations relies on reference intervals. Physiological changes in pregnancy may result in significant changes in normal values for many biochemical assays, and as such results may be misinterpreted as abnormal or mask a ...
Morton, Adam, Teasdale, Stephanie
core   +2 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Early pregnancy diagnosis by measurement of pregnancyassociated glycoproteins (PAGs) in blood serum and milk of dairy cows

open access: yesЖивотновъдни науки, 2023
The present study aimed to determine the efficiency of two commercial ELISA tests for measuring pregnancy-associated glycoproteins (PAGs) in blood serum and milk in relation to early pregnancy diagnosis in lactating Holstein-Friesian cows.
Nasko Vasilev   +3 more
doaj  

Preliminary data for performance in hue ordering tests during pregnancy

open access: yesBrazilian Journal of Medical and Biological Research, 2019
The visual system of women changes during pregnancy. Few reports have addressed the effects of pregnancy on color vision. We aimed to compare the color vision of women in the first, second, and third trimesters of pregnancy. Fifty women were divided into
T.S.S. Calandrini   +6 more
doaj   +1 more source

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