Results 41 to 50 of about 2,212,500 (210)

Investigation of DNA repair in human oocytes and preimplantation embryos [PDF]

, 2010
DNA repair genes are expressed in mammalian embryos and in human germinal vesicles, however, little is known about DNA repair in human preimplantation embryos.
Jaroudi, S.
core  

Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population.

Journal of Biochemical and Clinical Genetics, 2019
Background: Couples who are at risk for having an infant with a serious genetic disorder can benefit from pre-implantation genetic diagnosis (PGD), but many couples still opt for the riskier pre-natal diagnosis (PND). Although couples make this decision
Fawz AlHarthi, Moeen Al Sayed, Ahmed Yaqinuddin, Gulsan Abubakar Karbani, Ameera Salem Blobaid, Monika Maya Wahi   +5 more
doaj   +1 more source

Does stereoelectroencephalographic depth electrode insertion alter seizure frequency? A baseline versus endpoint analysis

Epilepsia, EarlyView.
Abstract The implantation effect refers to a transient reduction in seizure frequency following intracranial electrode insertion in patients with epilepsy, independent of therapeutic intervention. This retrospective study examined potential clinical and demographic predictors of the implantation effect in 51 patients who underwent ...
Shreyashish Roy‐Chowdhury, Jorge G. Burneo, Juan Toro‐Perez, David A. Steven, Michelle Lee‐Jones, Keith MacDougall, Jonathan Lau, Richard S. McLachlan, Ana Suller Marti   +8 more
wiley   +1 more source

Comparative multicenter evaluation of thalamic neuromodulation for treatment‐resistant epilepsy in children

Epilepsia, EarlyView.
Abstract Objective Use of neuromodulation strategies targeting thalamic nuclei, including deep brain stimulation (DBS) and responsive neurostimulation (RNS), for treatment of pediatric drug‐resistant epilepsy (DRE) is increasing, despite limited evidence for efficacy and safety. We present the initial results from the Comparative Multicenter Evaluation
Samuel A. Tenhoeve, Nebras M. Warsi, Allison M. Ludwick, Adam C. Glaser, Marcella R. Ruppert‐Gomez, Scellig S. Stone, Megan Votoupal, Jeffrey S. Raskin, Shanique Doyle, Benjamin Kennedy, Deborah Grenard, Dominic Nistal, Hannah E. Goldstein, Jason S. Hauptman, Gavin Yoon, Kurtis I. Auguste, David D. Gonda, Alon Kashanian, Shaun D. Rodgers, Janette Coble, Jarod L. Roland, Nunthasiri Wittayanakorn, Chima O. Oluigbo, Somnath Das, Jasmine A. Thum, Carolina Gorodetsky, MyLoi Huynh, George M. Ibrahim, Robert J. Bollo   +28 more
wiley   +1 more source

Supporting couples with polycystic kidney disease in a medically assisted reproduction process

Giornale di Clinica Nefrologia e Dialisi
Preimplantation diagnosis process for couples with polycystic kidney disease involves several steps: genetic and gynecological counseling, in vitro fertilization (IVF/ICSI), embryo biopsy, genetic analysis, selection of healthy embryos and implantation.
Daniela Zuccarello, Claudia Livi, Valentina Zicaro, Sara Communci, Ludovica Picchetta   +4 more
doaj   +1 more source

Electroclinical features and dynamic network connectivity of orbitofrontal epilepsy

Epilepsia, EarlyView.
Abstract Objective Orbitofrontal epilepsy (OFE) is rare and underrecognized. This study aims to characterize electroclinical features and dynamic network connectivity of OFE and subtypes. Methods We retrospectively analyzed 17 patients with OFE who underwent stereoelectroencephalographic (SEEG) electrode implantation and epilepsy surgery at our center.
Meixuan Ren, Cuiping Xu, Na Clara Pan, Runshi Gao, Wei Shu, Xueyuan Wang, Xi Zhang, Li Wang, Liping Zhang, Xiaoming Yan, Xiaohua Zhang, Tao Yu, Mohamad Z Koubeissi, Yuping Wang   +13 more
wiley   +1 more source

Choosing embryos: Ethical complexity and relational autonomy in staff accounts of PGD [PDF]

, 2007
Copyright @ 2008 the authors. This article is available in accordance with the Creative Commons Deed, Attribution 2.5, see http://creativecommons.org/licenses/by-nc-nd/2.5/deed.en_CA.The technique of preimplantation genetic diagnosis (PGD) is commonly ...
Williams, C, Clare Williams, Sandall, Jane; id_orcid, Jane Sandall (3213219), Kathryn Ehrich (16049615), Kathryn Ehrich, Bobbie Farsides, Bobbie Farsides (4461928), Sandall, J, Rosamund Scott, Jane S, Scott, R, Rosamund Scott (16049618), Jane Sandall, Farsides, Bobbie, Ehrich, K, Ehrich, Kathryn, Williams, Clare, Clare Williams (14068554), Farsides, B, Scott, Rosamund   +20 more
core   +1 more source

Targeting myotonic dystrophy by preimplantation genetic diagnosis-karyomapping

Taiwanese Journal of Obstetrics & Gynecology, 2019
Objective: To report a case with Myotonic dystrophy type I with successful preimplantation genetic diagnosis-karyomapping. Case report: A 34-year-old female carrier of myotonic dystrophy type I was treated at our clinic with a successful pregnancy after ...
Cheng-Wei Wang, Yung-Liang Liu, Chi-Huang Chen   +2 more
doaj   +1 more source

Whole exome sequencing identifies a novel FRAS1 mutation and aids in vitro fertilization with preimplantation genetic diagnosis in Fraser syndrome

Taiwanese Journal of Obstetrics & Gynecology, 2022
Objective: To demonstrate the picture of a woman who had three times of pregnancies but fetuses were complicated with Fraser syndrome, a rare genetic disorder with multiple congenital anomalies.
Tsung-Ying Ou, Meng-Che Tsai, Pao-Lin Kuo, Ni-Chung Lee, Yen-Yin Chou   +4 more
doaj   +1 more source

Perils and progress in epilepsy surgery utilization: Twenty‐five years later

Epilepsia, EarlyView.
Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley   +1 more source