Results 71 to 80 of about 22,286 (215)

Inflammatory Cytokines as Early Predictors of Weaning Failure From Extracorporeal Life Support

Artificial Organs, EarlyView.
Levels of IL‐8 and IL‐6 and their dynamics are reliable early predictors of ECLS weaning failure. ABSTRACT Background Weaning from extracorporeal life support (ECLS) in patients with refractory shock still remains a complex decision. Despite considerable advances in ECLS management, reliable biomarkers to predict weaning success are still not available.
Kostiantyn Kozakov, Alois Philipp, Maik Foltan, Anton Heller, Dzmitry Turtsevich, Christian Schach, Peter‐Paul Ellmauer, Walter Petermichl, Bernhard Flörchinger, Christof Schmid, Simon Schopka, Zdenek Provaznik   +11 more
wiley   +1 more source

Elevated sperm DNA fragmentation is correlated with an increased chromosomal aneuploidy rate of miscarried conceptus in women of advanced age undergoing fresh embryo transfer cycle

Frontiers in Endocrinology
BackgroundMale sperm DNA fragmentation (SDF) may be associated with assisted reproductive technology (ART) outcomes, but the impact of SDF on the occurrence of aneuploid-related miscarriage remains controversial.MethodsGenome-wide single-nucleotide ...
Wanting Fu, Wanting Fu, Wanting Fu, Wanting Fu, Qiuying Cui, Qiuying Cui, Qiuying Cui, Qiuying Cui, Zhiqin Bu, Zhiqin Bu, Zhiqin Bu, Zhiqin Bu, Hao Shi, Hao Shi, Hao Shi, Hao Shi, Qingling Yang, Qingling Yang, Qingling Yang, Qingling Yang, Linli Hu, Linli Hu, Linli Hu, Linli Hu   +23 more
doaj   +1 more source

Customizing Conception: A Survey of Preimplantation Genetic Diagnosis and the Resulting Social, Ethical, and Legal Dilemmas [PDF]

, 2002
One in six American couples experience difficulties conceiving a child. With fertility rates at an all time low, the business of treating infertility is booming.
Roberts, Jason Christopher
core   +1 more source

False positive rate of an arrayCGH platform for single-cell preimplantation genetic screening and subsequent clinical application on day-3 [PDF]

, 2013
In this work, false positive rate of an arrayCGH platform for its use in day-3 single-blastomere analysis was calculated. For this purpose, 38 embryos diagnosed as abnormal on day-3 by FISH were re-biopsied on day-4.
Buendía Segura, Maria del Pilar, Mateu, Emilia, Mercader, Amparo, Milán-Sánchez, Miguel, Mir, Pere, Peinado Cervera, Vanessa, Pellicer Martínez, Antonio, Remohí Giménez, José, Rodrigo Vivó, Lorena, Rubio Lluesa, Carmen, Simón Vallés, Carlos   +10 more
core   +1 more source

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

Equine Veterinary Journal, EarlyView.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez, Alejandro de la Fuente, Kazuki Takahashi, Hugo Monteiro, Mauricio Mendes, Stuart Meyers, Pouya Dini   +6 more
wiley   +1 more source

A novel variation in DEPDC5 causing familial focal epilepsy with variable foci

Frontiers in Genetics
BackgroundDisheveled, EGL-10, and pleckstrin (DEP) domain-containing protein 5 (DEPDC5) is a component of GTPase-activating protein (GAP) activity toward the RAG complex 1 (GATOR1) protein, which is an inhibitor of the amino acid-sensing branch of the ...
Yanchi Wang, Yanchi Wang, Yanchi Wang, Yanchi Wang, Wenbin Niu, Wenbin Niu, Wenbin Niu, Wenbin Niu, Hao Shi, Hao Shi, Hao Shi, Hao Shi, Xiao Bao, Xiao Bao, Xiao Bao, Xiao Bao, Yidong Liu, Yidong Liu, Yidong Liu, Yidong Liu, Manman Lu, Manman Lu, Manman Lu, Manman Lu, Yingpu Sun, Yingpu Sun, Yingpu Sun, Yingpu Sun   +27 more
doaj   +1 more source

Preimplantation Genetic Diagnosis in Europe [PDF]

, 2007
In vitro fertilisation (IVF) and preimplantation genetic diagnosis (PGD) are now well-established treatments and are provided in many European countries.
ANTIÑOLO Guillermo, CORVELEYN Anniek, DEQUEKER Elisabeth, LAWFORD DAVIES James, MORRIS Michael, PALAU Francesc, SCHMUTZLER Andreas, ZIKA Eleni   +7 more
core  

Singleton birth after preimplantation genetic diagnosis for Huntington disease using whole genome amplification [PDF]

, 2009
Objective: To report a successful case of preimplantation genetic diagnosis (PGD) for Huntington disease using whole genome amplification. Design: Case report. Setting: University assisted reproduction unit.
Chow, JFC, Ho, PC, Lam, STS, Lau, EYL, Ng, EHY, Tong, T, Yeung, WSB   +6 more
core   +1 more source

Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley   +1 more source

A novel isolator-based system promotes viability of human embryos during laboratory processing [PDF]

, 2012
In vitro fertilisation (IVF) and related technologies are arguably the most challenging of all cell culture applications. The starting material is a single cell from which one aims to produce an embryo capable of establishing a pregnancy eventually ...
A Davidson, A Mantzouratou, AH Goldstein, Alison Murdoch, B Dale, B Kea, B Kovacic, B Midcalf, Bruce Watson, CA Coleman, D Rizos, DBG Sobrinho, DP John, ER Maher, FS Veraitch, GL Harton, H Niemann, HD Morgan, HJ Leese, HN Ciray, J Cohen, J Hall, JC Dumoulin, JE Buster, JE Swain, JE Swain, Jeanette Fenwick, JM Bland, John Rhodes, K Cockburn, KP Phillips, KP Phillips, L Caprino, L Karagenc, L Molhave, L Plante, L Tillett, LE Young, Louise Hyslop, Lynne Nowak, M Lane, M Lane, Mary Herbert, Nilendran Prathalingam, P Bowman, PA Almeida, RL Brinster, RM Rivera, Robin Henderson, Samantha Byerley, Shree Ram Singh, SJ Pickering, Steve Harbottle, TA Griffiths, WA Kues, WH Wang, Y Xie   +56 more
core   +8 more sources