Results 111 to 120 of about 724,987 (327)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Understanding prejudice of psychic suffering individuals about sexuality

open access: yesRevista Brasileira de Enfermagem
Objectives: to understand the conceptions of individuals in psychological distress about their sexuality. Methods: qualitative study held at a Psychosocial Care Center. Fifteen people assisted in the service participated. A semi-structured questionnaire
Gisela Cardoso Ziliotto   +1 more
doaj   +1 more source

O preconceito sexual internalizado por homossexuais masculinos

open access: yesInteração em Psicologia, 2010
Despite the emergence, in the last decades, of a wide range of studies related to homosexuality, little has been produced on the subject of internalized prejudice.
Adriana Nunan   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The Structure of Prejudice and Its Relation to Party Preferences in Belgium: Flanders and Wallonia Compared

open access: yesPsychologica Belgica, 2017
We test two assumptions of the generalized prejudice literature. First, that the structure of generalized prejudice (i.e. how prejudices are interrelated) is dependent on the intergroup context.
Cecil Meeusen   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Menorah Review (No. 47, Fall, 1999) [PDF]

open access: yes, 1999
Physician-Assisted Suicide -- What Price Prejudice? -- The American Synagogue: Now and Then -- Amelek -- Picks and Pans from the Feminist\u27s Corner -- King David -- A Good Life Now and Then -- Noteworthy ...

core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

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