Results 91 to 100 of about 65,072 (307)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

innovation, employee control, efficiency, resistance to social change, dirty work

Bulletin of the Transilvania University of Braşov: Series VII: Social Sciences, Law
This article presents the theoretical framework and the results of a research conducted in a brewery with respect to the concept of gender discrimination. The main objective of the research is to identify gender inequalities and
Ada Ioana Dobrescu
doaj   +1 more source

Development and functions of prejudices

, 2017
Vorurteile haben vielschichtige Entstehungsursachen und können unterschiedliche Funktionen erfüllen. Diese Arbeit beschreibt hermeneutisch eine Auswahl der zahlreichen verschiedenen Entstehungsmöglichkeiten und geht insbesondere auf zwei Bereiche in der ...
Hafner, Jana
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The Hippocratic Oath: the Transformation of its Semantics and the Revival of its Pragmatics [PDF]

SCHOLE, 2015
The Hippocratic Oath enjoys imperishable value in the western traditions of medicine. In modern culture, its postulates have frequently been interpreted as the foundations for the principles of bioethics and a basis of paternalistic practice, typical for
Melik-Gaykazyan, Irina, Mescheryakova, Tamara   +1 more
doaj  

Parents' Estimates of Children's Racial Prejudices [PDF]

Previous research suggests that racial prejudice emerges in the early preschool years, often influenced by parental attitudes. However, many parents, particularly White parents, may be unaware that their children hold racial biases.
Dominici, Caitly A.
core  

Tyrants Of The Soul: Prejudices In French Revolutionary Education, 1789-1799

, 2017
Through analyzing textbooks, educational pamphlets, and the correspondence of the Committee of Public Instruction, I show that prejudices became the object of critique in the era of the Enlightenment and were a continuing topic of political concern ...
Hannah N Malcolm (22015094)
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source