Results 101 to 110 of about 65,072 (307)

Prejudices: An Investigation Into Barriers of Humanity [PDF]

open access: yes, 2014
By bringing people closer together, the phenomenon of globalisation not only accentuates differences but also it reinforces the sense of identity and belonging.
Gueye, Cheikh Mbacké
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Female Founding: An Institutional Theory Perspective on the Effect of Gender-Specific Prejudices in Germany [PDF]

open access: yes
This research is focused on whether female entrepreneurs face institutional discrimination based on prejudices. Therefore, in consideration of the institutional theory, this paper aims to clarify how informal institutions, such as norms, values and ...
Westarp, Natalie   +2 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Toward the categorization of online political prejudices: The case of New Brunswick 2020 Provincial Election [PDF]

open access: yes
This paper is qualitative case study of political prejudices on the internet. Negative social media remarks received by candidates in the 2020 New Brunswick provincial election were analyzed.
McLaughlin, Gilbert
core   +1 more source

New Worlds and Old Prejudices: Australia, Cricket and the Subcontinent: 1880-1960

open access: yes, 2022
New Worlds and Old Prejudices: Australia, Cricket and the Subcontinent: 1880 ...
Tom Heenan (13384635)   +1 more
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Tyrants Of The Soul: Prejudices In French Revolutionary Education, 1789-1799 [PDF]

open access: yes, 2016
Through analyzing textbooks, educational pamphlets, and the correspondence of the Committee of Public Instruction, I show that prejudices became the object of critique in the era of the Enlightenment and were a continuing topic of political concern ...
Malcolm, Hannah   +1 more
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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