Results 71 to 80 of about 305,369 (273)

Beverly Daniel Tatum, Ph.D. Why are all the black kids sitting together in the cafeteria? And other conversations about race. Basic Books, 1997 [PDF]

open access: yes, 2008
Why Are All the Black Kids Sitting Together in the Cafeteria? by Beverly Daniel Tatum is a comprehensive guide that explores several main points and the distinct complexities of race-related topics. Tatum discusses where the idea of race came from, what
Guarino, Alex
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

College Student Perceptions of Varying Disability Types: Does Contact Experience Matter? [PDF]

open access: yes, 2019
Studies exploring prejudices between groups have suggested that contact is related to attitudes. This relationship has been studied in the context of attitudes toward people with disabilities and has yielded inconsistent results. Other variables, such as
Anderson, Gianna
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Dispelling the Myths About the Battered Woman\u27s Defense: Towards a New Understanding [PDF]

open access: yes, 1992
This essay explores the growth of the use of self-defense by battered women from a historical perspective in order to explain the magnitude of the prejudices these defendants face.
Dowd, Michael
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Evaluating Maintainability Prejudices with a Large-Scale Study of Open-Source Projects

open access: yes, 2018
Exaggeration or context changes can render maintainability experience into prejudice. For example, JavaScript is often seen as least elegant language and hence of lowest maintainability.
B Ray   +13 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The Roles of Ethnic Theater in Immigrant Communities in the United States 1850-1930 [PDF]

open access: yes, 1981
In the late nineteenth and early twentieth centuries millions of Europeans left their homes to form immigrant communities in the United States. Much of the literature about those immigrant communities focuses upon problems such as their ecomonic ...
Seller, Maxine S.
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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