Results 201 to 210 of about 4,442,346 (285)

Leveraging prompt-driven generative AI for systematic reviews in digital psychiatry: A stage-matched comparative proof-of-concept for healthcare researchers and clinicians. [PDF]

PLOS Digit Health
Parkington K, Joseph JT, Musleh K, Rouleau-Tang M, Persaud A, Rueda A, Teferra BG, Al-Shamali HF, Mao W, Nezhad FG, Burback L, Zhang Y, Jetly R, Vermetten E, Monson C, Krishnan S, Zeifman RJ, Greenshaw A, Lou W, Bhat V.   +19 more
europepmc   +1 more source

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

Advanced Science, EarlyView.
In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang, Hongjie Gao, Bifei Zhang, Xuetian Li, Ding Li, Aihua Cao, Fengyin Sun   +6 more
wiley   +1 more source

Letter to "Early Night-Time Bracing for Mild Adolescent Idiopathic Scoliosis: A Retrospective Cohort Study". [PDF]

Global Spine J
Wu X, Gu C.
europepmc   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

Preliminaries and pioneers: framing the questions

, 2018
openaire   +2 more sources

Virtual Money and Emotional Reality: A Qualitative Analysis of Symbolic Issues in a Stock Market Simulation. [PDF]

Behav Sci (Basel)
Finet A, Kristoforidis K, Laznicka J.
europepmc   +1 more source

Preliminary Questions in the Netherlands : Questions from Lower Courts to the Dutch Supreme Court

Ritsumeikan Law Review
Krans, H.B., Ploum, M.J.R.
openaire   +2 more sources

A Modular Standard Operating Procedure for Standardizing Lithium Metal Interfaces

Advanced Science, EarlyView.
A modular standard operating procedure (SOP) is developed to standardize lithium metal interfaces through sequential etching, brushing, and soaking. By transforming poorly controlled lithium surfaces into chemically uniform and structurally regulated interfaces, the framework improves electrochemical reproducibility, interfacial stability, and ...
Wen‐Hsin Chang, Anlin Shaju, Han‐Shiuan Lin, Sih‐Ling Hsu, Quang Huy Dinh, Che‐Ning Yeh, Elise Yu‐Tzu Li, Yu‐Sheng Su   +7 more
wiley   +1 more source

A Coordinated Approach to Perioperative Rehabilitation to Enhance Outcomes in Melanoma: Protocol for the CARE-Melanoma Pilot Randomized Controlled Trial. [PDF]

JMIR Res Protoc
Smith-Turchyn J, Hvizd JL, Francescutti V.   +2 more
europepmc   +1 more source

A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43

Advanced Science, EarlyView.
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg, Anastasia Lopatina, Hao Ruan, Tom Scheidt, Simone Mosna, Emre Pekbilir, Julia Bieber, Frank Schäfer‐Depoix, Katharina Landfester, Carla Schmidt, Martin M. Möckel, Svenja Morsbach, Friederike Schmid, Dorothee Dormann, Lukas Stelzl, Martin Girard, Edward A. Lemke   +16 more
wiley   +1 more source