Advanced Science, EarlyView.Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng +19 more
wiley +1 more source
Advanced Science, EarlyView.In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu +7 more
wiley +1 more source
A comparative study of the performance of different large language models in the Chinese National Pharmacist Licensing Examination. [PDF]
Front Med (Lausanne)Huang C, Sun Y, Liu W.
europepmc +1 more source
From local control to immune synergy: the evolving role of stereotactic body radiotherapy in the immunotherapy era of hepatocellular carcinoma. [PDF]
Hepatobiliary Surg NutrYan Z, Hou X, Zhang F.
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Comment on "Association of Proton Pump Inhibitor and Potassium-Competitive Acid Blocker Use With Discontinuation and Intolerance of Oral 5-Aminosalicylic Acid in Patients With Ulcerative Colitis". [PDF]
J Gastroenterol HepatolFatima B.
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MCID, SCB, and PASS Thresholds After Percutaneous Trigger Finger Release With or Without Corticosteroid Injection. [PDF]
J Clin MedKarasu R, Dinç M, Eken G.
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Animal models of gut microbiota-male reproductive interactions: methodological assessment, translational bottlenecks, and optimization strategies. [PDF]
Front Endocrinol (Lausanne)Ma Y, Diao X, Wang Z.
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CAR T before the storm: early consolidation in B-ALL. [PDF]
Blood AdvShouval R, Muffly L.
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