Results 181 to 190 of about 388,380 (262)

Lowering the Barrier to Surgical Research: Can Artificial Intelligence (AI) Support Trainees? [PDF]

ANZ J Surg
Rouse M, Kaleem Y, Yeung JM.
europepmc   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Preliminary Questions in the Netherlands : Questions from Lower Courts to the Dutch Supreme Court

Ritsumeikan Law Review
Krans, H.B., Ploum, M.J.R.
openaire   +2 more sources

Comment on "Can psychological interventions affect cardiac rehabilitation patients' well-being? Preliminary results from a longitudinal study". [PDF]

Int J Cardiol Cardiovasc Risk Prev
Saha M, Sharat Vishwanath K.
europepmc   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

A Dialogic Participatory Model Between Professionals and Patients for the Co-Creation of Transitioning Care Management Programmes in Rare Bone Diseases. [PDF]

Health Expect
Mordenti M, Forni S, Grippa E, Forgia MC, Scognamiglio D, Boarini M, Massa G, Romeo A, Sergi A, Sangiorgi L, Transitioning Care Management Working Group (TCM WG).   +10 more
europepmc   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

Advanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu, Shimin Jiang, Zhenkun Yang, Shunlai Shang, Jiayi Li, Guming Zou, Cheng Zhou, Wenge Li   +7 more
wiley   +1 more source

Informational needs in vulvar cancer and precursor conditions: a social listening study. [PDF]

Support Care Cancer
Wouters D, van Lynden van Sandenburg MVGL, Hulscher KK, van Esch EMG, Aarts JWM.   +4 more
europepmc   +1 more source