Results 61 to 70 of about 227,636 (286)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

The Advocates General at the General Court

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2025 10(3), 863-875 | Article | (Table of Contents) 1. Introduction. – 2. Setting the stage: two courts ut one procedure. – 3.
Tamara Capeta
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

The Dialogue Between the Courts Revisited: An Analysis of National Preliminary References and Their Impact on Advancing CJEU Case Law on Religious Discrimination

Zbornik Znanstvenih Razprav
This article explores the dialogue between the CJEU and national courts on the scope and meaning of religious discrimination under Framework Directive 2000/78/EC.
Jule Mulder
doaj   +1 more source

‘“Grow Up!”: Rethinking the Preliminary Reference Procedure from the Perspective of Maturity’

LSE Law Review, 2021
The clash between the German Constitutional Court and the CJEU in May 2020 over economic policy highlights the growing tension between the EU and the courts of last instance in Member States. This article argues that such tensions demand a legal order which respects national judicial hierarchies, and thereby becoming mature.
openaire   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Procedeu de determinare rapidă a speciilor de Candida în medicamente

One Health & Risk Management, 2023
PROCEDURE FOR RAPID DETERMINATION OF CANDIDA SPECIES IN DRUGS Introduction. The contamination of drugs with unauthorized microorganisms poses a significant risk in the pharmaceutical industry, as it has the potential to compromise product integrity ...
Nicolae PUȘCAȘ, Greta BĂLAN
doaj  

Preliminary reference procedure within the scope of European judicial system

, 2007
The thesis deals with the preliminary reference procedure. There is outlined not only the characteristic of this procedure or its evolution, but also the interpretation of the term "court or tribunal of a Member State" or the Exceptions to the Duty to ...
Zvárová, Daniela
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

EU Procedural Law Revisited: The Reformed EU Judicial Architecture between the Statute of the Court of Justice and the Rules of Procedure

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2025 10(2), 293-326 | Article | (Table of Contents) 1. Introduction: scope and purposes of the analysis. – 2.
Lorenzo Grossio, Davor Petrić
doaj   +1 more source