Premature Deindustrialization [PDF]
I document a significant deindustrialization trend in recent decades that goes considerably beyond the advanced, post-industrial economies. The hump-shaped relationship between industrialization (measured by employment or output shares) and incomes has shifted downwards and moved closer to the origin.
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Premature Ovarian Failure Is Not Premature Menopause
Abstract: Normal menopause occurs at an average age of 50 and results from ovarian follicle depletion. Normal menopause is an irreversible condition, whereas premature ovarian failure is characterized by intermittent ovarian function in half of these young women.
Kalantaridou, S. N., Nelson, L. M.
openaire +4 more sources
Stops making sense: translational trade-offs and stop codon reassignment [PDF]
Background Efficient gene expression involves a trade-off between (i) premature termination of protein synthesis; and (ii) readthrough, where the ribosome fails to dissociate at the terminal stop. Sense codons that are similar in sequence to stop codons
A Eyre-Walker+33 more
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High rate of SARS-CoV2 nonsense spike genomes coding for prematurely truncated proteins [PDF]
Replication of SARS-CoV2 virions is an error-prone process which may eventually generate a percentage of impaired protein copies with complete lack of functionality. For instance, after RNA mis-replication, a very premature stop codon (UAG, UAA, UGA) coding for a prematurely truncated (nonsense-mutated) spike protein may occur.
arxiv
Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson–Gilford Progeria Syndrome [PDF]
Hutchinson–Gilford progeria syndrome (HGPS) is a genetic disorder characterized by premature aging features. Cells from HGPS patients express progerin, a truncated form of Lamin A, which perturbs cellular homeostasis leading to nuclear shape alterations,
Aguado J.+12 more
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Genetic algorithms for the generation of models with micropopulations [PDF]
Proceedings of: EvoWorkshops 2003: EvoBIO, EvoCOP, EvoIASP, EvoMUSART, EvoROB, and EvoSTIM Essex, UK, April 14–16, 2003The present article puts forward a method for an interactive model generation through the use of Genetic Algorithms applied to small ...
Isasi, Pedro+3 more
core +3 more sources
Geometrical destabilization, premature end of inflation and Bayesian model selection [PDF]
By means of Bayesian techniques, we study how a premature ending of inflation, motivated by geometrical destabilization, affects the observational evidences of typical inflationary models. Large field models are worsened, and inflection point potentials are drastically improved for a specific range of the field-space curvature characterizing the ...
arxiv +1 more source
A Profile of Premature Birth in Erie County [PDF]
Produced by the United Way of Buffalo & Erie County and the United Way Healthy Start, Healthy Future for All Coalition, this report examines why it is important to reduce premature birth in Erie County.
United Way Healthy Start, Healthy Future for All Coalition+1 more
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Real Time Monitoring and Control of Neonatal Incubator using IOT [PDF]
The care of new born babies are the most important and sensitive part of bio-medical domain. Some new born babies have a higher risk of mortality due to their gestational age or their birth weight. Most of the premature babies born on 32-37 weeks of gestation and are deceased due to their unmet need for warmth.
arxiv
Improvements of real coded genetic algorithms based on differential operators preventing premature convergence [PDF]
This paper presents several types of evolutionary algorithms (EAs) used for global optimization on real domains. The interest has been focused on multimodal problems, where the difficulties of a premature convergence usually occurs. First the standard genetic algorithm (SGA) using binary encoding of real values and its unsatisfactory behavior with ...
arxiv +1 more source