Results 61 to 70 of about 1,793,209 (389)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Evaluation of surfactant replacement therapy effects: A new potential role of lung ultrasound [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2015
Introduction. Previous studies suggested that effects of the surfactant administration in preterm infants with respiratory distress syndrome cannot be followed by lung ultrasound (L-US). Objective.
Lovrenski Jovan   +4 more
doaj   +1 more source

Ambient PM2.5 exposure and expected premature mortality to 2100 in India under climate change scenarios

open access: yesNature Communications, 2018
Premature mortality from current ambient fine particulate (PM2.5) exposure in India is large, but the trend under climate change is unclear. Here we estimate ambient PM2.5 exposure up to 2100 by applying the relative changes in PM2.5 from baseline period
S. Chowdhury, S. Dey, Kirk R. Smith
semanticscholar   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

Environmental noise exposure, early biological risk and mental health in nine to ten year old children: a cross-sectional field study

open access: yesEnvironmental Health, 2011
Background Previous research suggests that children born prematurely or with a low birth weight are more vulnerable to the mental health effects of ambient neighbourhood noise; predominantly road and rail noise, at home.
Stansfeld Stephen A   +2 more
doaj   +1 more source

Non-perforated cardiac tamponade associated with a central venous catheter in a premature infant with extremely low birth weight

open access: yesTrends in Pediatrics, 2023
Central venous catheterization is almost routinely used in neonatal intensive care, especially in premature and extremely low-birth-weight infants. One of the rare but life-threatening complications is pericardial effusion and cardiac tamponade.
Sedef Öksüz   +6 more
doaj   +1 more source

Maternal morbidity associated with violence and maltreatment from husbands and in-laws: findings from Indian slum communities. [PDF]

open access: yes, 2016
BackgroundIntimate partner violence (IPV) victimization is linked to a broad range of negative maternal health outcomes. However, it is unclear whether IPV is directly related to poor maternal outcomes or whether IPV is a marker for other forms of ...
Balaiah, Donta   +9 more
core   +2 more sources

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra   +17 more
wiley   +1 more source

FAKTOR­-FAKTOR RISIKO TERJADINYA ASFIKSIA NEONATORUM DI RSD JOMBANG PERIODE 1 JANUARI ­- 31 DESEMBER 2007 [PDF]

open access: yes, 2009
Neonatal Asphyxia is an emergency condition when the baby failed to breath spontaneously and regularly after they were born. Neonatal asphyxia remains the main cause of neonatal mortality as well as permanent neurological abnormality.
SUNDARI TIKA, TRI
core  

Reflection on modern methods: years of life lost due to premature mortality—a versatile and comprehensive measure for monitoring non-communicable disease mortality

open access: yesInternational Journal of Epidemiology, 2019
The analysis of causes impacting on premature mortality is an essential function of public health surveillance. Diverse methods have been used for accurately assessing and reporting the level and trends of premature mortality; however, many have ...
Ramón Martínez   +3 more
semanticscholar   +1 more source

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