Results 61 to 70 of about 850,132 (317)

Frequent Ventricular Premature Complex-Induced Decompensated Heart Failure

, 2015
Asymptomatic premature ventricular beats are most common presentation form of arrhyth-mia observed in patients with or without structural heart disease. In long term, frequent pre-mature ventricular beats can lead left ventricule failure in structurally ...
Hüseyin Ede, Bașar Candemir, Çetin Erol, Veysel Kutay Vurgun, Ali Timuçin Altın, Ömer Akyürek   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Evaluation of surfactant replacement therapy effects: A new potential role of lung ultrasound [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2015
Introduction. Previous studies suggested that effects of the surfactant administration in preterm infants with respiratory distress syndrome cannot be followed by lung ultrasound (L-US). Objective.
Lovrenski Jovan, Sorantin Erich, Stojanović Sanja, Doronjski Aleksandra, Lovrenski Aleksandra   +4 more
doaj   +1 more source

Premature burial

Forensic Science, Medicine and Pathology, 2023
AbstractThe fear of being buried alive or taphophobia remains a significant concern for a number of individuals. In previous centuries however, reports of live burials were frequently promulgated in the media fostering an industry focused around the manufacturing and selling of security coffins which either facilitated egress or enabled the recently ...
openaire   +2 more sources

Retrospective Analysis of Cases with Premature Thelarche

, 2020
Objective:Premature thelarche is defined as breast enlargement in females (younger than eight years) without other signs of secondary gender character development.
Teoman Akçay, Hasan Serdar Kıhtır
core   +1 more source

Neonatologie/Pädiatrie – Leitlinie Parenterale Ernährung, Kapitel 13 [PDF]

, 2009
There are special challenges in implementing parenteral nutrition (PN) in paediatric patients, which arises from the wide range of patients, ranging from extremely premature infants up to teenagers weighing up to and over 100 kg, and their varying ...
Jochum, F., Fusch, C., Böhles, H. J., Krohn, K., Fusch, Christoph, Jochum, Frank, Fusch, C, Krawinkel, M, Krawinkel, M., Böhles, HJ, Böhles, Hansjosef, Mühlebach, S., Krohn, K, Bauer, K, Koletzko, B, Working group for developing the guidelines for parenteral nutrition of The German Society for Nutritional Medicine, Mühlebach, S, Krohn, Kathrin, Bauer, Karl, Working group for developing the guidelines for parenteral nutri,, Mühlebach, Stefan, Koletzko, Berthold, Krawinkel, Michael, Bauer, K., Jochum, F, Koletzko, B.   +25 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Environmental noise exposure, early biological risk and mental health in nine to ten year old children: a cross-sectional field study

Environmental Health, 2011
Background Previous research suggests that children born prematurely or with a low birth weight are more vulnerable to the mental health effects of ambient neighbourhood noise; predominantly road and rail noise, at home.
Stansfeld Stephen A, Clark Charlotte, Crombie Rosanna   +2 more
doaj   +1 more source