Results 71 to 80 of about 1,301,542 (365)
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Improvements of real coded genetic algorithms based on differential operators preventing premature convergence [PDF]
Advances in Engineering Software, 35 (3-4), 237-246, 2004, 2009 This paper presents several types of evolutionary algorithms (EAs) used for global optimization on real domains. The interest has been focused on multimodal problems, where the difficulties of a premature convergence usually occurs. First the standard genetic algorithm (SGA) using binary encoding of real values and its unsatisfactory behavior with ...
arxiv +1 more source
Joint versus separate inpatient rehabilitation treatment for patients with alcohol use disorder or drug use disorder : an observational study [PDF]
, 2018 Background: In many national treatment systems, patients with alcohol use disorders (AUD) and those with drug use disorders (DUD) are treated separately, while other systems provide joint treatment for both kinds of substance use disorders (SUDs ...
Bender, Stefan +7 more
core +1 more source
Germline variants in CDKN2A wild‐type melanoma prone families
Molecular Oncology, EarlyView.Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen +5 more
wiley +1 more source
What is a premature death? [PDF]
, 2007 The one who dies is deprived of goods that this person would have enjoyed if he or she had continued living, according to the popular “deprivation account of harm.” The person who dies “prematurely” is generally thought to suffer the most harm from death.
Trisel, Brooke Alan
core
Stops making sense: translational trade-offs and stop codon reassignment [PDF]
, 2011 Background Efficient gene expression involves a trade-off between (i) premature termination of protein synthesis; and (ii) readthrough, where the ribosome fails to dissociate at the terminal stop. Sense codons that are similar in sequence to stop codons
A Eyre-Walker +33 more
core +4 more sources
Premature Switching in Graphene Josephson Transistors [PDF]
, 2009 We investigate electronic transport in single layer graphene coupled to superconducting electrodes. In these Josephson transistors, we observe significant suppression in the critical current Ic and large variation in the product IcRn in comparison to theoretic predictions in the ballistic limit.
arxiv +1 more source
Immortal Tracker: Tracklet Never Dies [PDF]
arXiv, 2021 Previous online 3D Multi-Object Tracking(3DMOT) methods terminate a tracklet when it is not associated with new detections for a few frames. But if an object just goes dark, like being temporarily occluded by other objects or simply getting out of FOV, terminating a tracklet prematurely will result in an identity switch.
arxiv
Indian Journal of Urology, 2007 Premature ejaculation (PE) is a common male sexual disorder. Recent normative data suggests that men with an intravaginal ejaculatory latency time (IELT) of less than 1 minute have "definite" PE, while men with IELTs between 1 and 1.5 minutes have "probable" PE.
openaire +3 more sources
Cuidados de prevenção e seguimento de nascidos prematuros - Ponto de vista do nefrologista pediatra
Residência Pediátrica, 2023 OBJECTIVE: Review renal and cardiovascular complications derived from premature births, to warn the pediatrician about preventive care and to recommend an approach toward the follow-up.
Michelle Toscan +3 more
doaj +1 more source