Results 71 to 80 of about 1,793,209 (389)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang +11 more
wiley +1 more source
Economic Burden of Legionnaires’ Disease, United States, 2014
Emerging Infectious Diseases, 2021 Through the use of published estimates of medical costs and new calculations of productivity losses, we estimate the lifetime economic burden of 2014 Legionnaires’ disease cases in the United States at ≈$835 million.
Madeleine Baker-Goering +3 more
doaj +1 more source
HNRNPK maintains epidermal progenitor function through transcription of proliferation genes and degrading differentiation promoting mRNAs. [PDF]
, 2019 Maintenance of high-turnover tissues such as the epidermis requires a balance between stem cell proliferation and differentiation. The molecular mechanisms governing this process are an area of investigation.
Chen, Yifang +8 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons +8 more
wiley +1 more source
Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3.
, 2019 Translation termination requires eRF1 and eRF3 for polypeptide-and tRNA-release on stop codons. Additionally, Dbp5/DDX19 and Rli1/ABCE1 are required; however, their function in this process is currently unknown.
Beissel , C. +5 more
core +1 more source
Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking. [PDF]
, 2020 Collagen is the most abundant protein in animals. Its dysregulation contributes to aging and many human disorders, including pathological tissue fibrosis in major organs.
Bai, Meirong +12 more
core +1 more source
Indian Journal of Urology, 2007 Premature ejaculation (PE) is a common male sexual disorder. Recent normative data suggests that men with an intravaginal ejaculatory latency time (IELT) of less than 1 minute have "definite" PE, while men with IELTs between 1 and 1.5 minutes have "probable" PE.
openaire +3 more sources
Association of the ICH Score With Withdrawal of Life‐Sustaining Treatment Over a 10‐Year Period
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The intracerebral hemorrhage (ICH) score was developed to enhance provider communication and facilitate early severity assessment. We examined the association of the ICH score with mortality and withdrawal of life‐sustaining treatment (WLST) in a large, multicenter stroke registry, and evaluated temporal trends in these associations.
Nina Massad +15 more
wiley +1 more source
Experiences of fathers with inpatient premature neonates: Phenomenological interpretative analysis
Iranian Journal of Nursing and Midwifery Research, 2018 Background: Birth and hospitalization of premature neonates create enormous challenges for the family with serious impacts on parents' mental and emotional health.
Tahmineh Dadkhahtehrani +3 more
doaj +1 more source
Statistical models of economic burden : a case study in medicine [PDF]
, 2019 Purpose: The main aim of this article is to use statistical methods for the estimation of the economic burden and the survival rate of deeply premature babies.
Gindullin, R. V. +3 more
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