Results 281 to 290 of about 214,960 (327)

Homelessness and Housing Instability Among Care Leavers in Australia: Exploring Housing Pathways and Best Practice Housing Models

Australian Journal of Social Issues, EarlyView.
ABSTRACT A significant proportion of young people exiting Out‐of‐Home Care (OOHC) encounter substantial challenges in securing housing, often leading to homelessness within a few months after leaving care. All Australian jurisdictions have now approved extended care programs up to 21 years; however, none of them currently offer these young people ...
Yujie Zhao, Jacinta Waugh
wiley   +1 more source

‘Playing the Game’: How Aboriginal Families Navigate Child Protection Systems to Restore Their Children Home From Out‐Of‐Home Care

Australian Journal of Social Issues, EarlyView.
ABSTRACT Reunification, or restoration of children from Out‐of‐Home Care (OOHC) is very rare. Using evidence generated from the New South Wales‐based Aboriginal‐led research Bring them home, keep them home, this paper examines and celebrates the resistance and resourcefulness of 20 Aboriginal families who navigated a child protection system designed to
B. J. Newton, Kimberly Chiswell, Caitlin Parker, Neika Tong, Shantelle Common   +4 more
wiley   +1 more source

Deaths of Children in Out‐of‐Home‐Care: What do Inquest Reports Reveal About the Framing of Child Protection Practice?

Australian Journal of Social Issues, EarlyView.
ABSTRACT In Western Australia (WA), a coronial inquest into the death of a child who had been in care is mandatory. An inquest is a public hearing, a fact‐finding process to determine the cause of the death, prevent future deaths from occurring in similar circumstances and to comment on the public health implications.
Celine Harrison, Maria Harries, Mark Liddiard   +2 more
wiley   +1 more source

SOX6 enhances vascular smooth muscle cell phenotypic switching and elevates blood pressure by activating autophagy

Animal Models and Experimental Medicine, EarlyView.
Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling, Xilan Dong, Liyan Mao, Chengjun Huang, Linjing Cong, Haizeng Zhang, Jun Cai, Zhenzhen Chen   +7 more
wiley   +1 more source

Senolytic treatment to rescue hallmarks of senescence in lymph node fibroblasts from patients with rheumatoid arthritis: Implications for premature aging and potential therapeutic intervention in early rheumatoid arthritis. [PDF]

Clin Exp Immunol
de Jong TA, Semmelink JF, Bolt JW, Grasso C, Hoebe RA, Krawczyk PM, van Baarsen LGM.   +6 more
europepmc   +1 more source

Comparative analysis of two newly established Cre rat lines, NeuN‐Cre and Thy1‐Cre, for neurological research

Animal Models and Experimental Medicine, EarlyView.
We generated two neuron‐specific Cre rat lines, Thy1‐Cre and NeuN‐Cre, using CRISPR/Cas9‐mediated targeted insertion. Both lines were validated for high neural specificity by crossing them with a Cre reporter rat. When bred with an ND1 conditional knockout rat, the two Cre lines produced distinct phenotypic outcomes. These rat lines have been deposited
Keru Li, Chenyang Liu, Gefan Wan, Lei Zhang, Rui Fan, Xu Zhang, Yuanlong Su, Jiayue He, Ning Liu, Feifei Guan, Wei Dong, Shan Gao, Weining Kong, Xiaolong Qi, Xiaolin Zhang, Yuanwu Ma   +15 more
wiley   +1 more source

Cpne7 deficiency induces cellular senescence and premature aging of dental pulp. [PDF]

Aging Cell
Lee YS, Park YH, Hwang G, Seo H, Ki SH, Bai S, Son C, Roh SM, Park SJ, Lee DS, Lee JH, Seo YM, Shon WJ, Jeon D, Jang M, Kim SG, Seo BM, Lee G, Park JC.   +18 more
europepmc   +1 more source

Dental fluorosis in the European roe deer (Capreolus capreolus): A review of the pathological changes in the enamel of fluorotic cheek teeth and the abnormal pattern of dental wear in affected dentitions

The Anatomical Record, EarlyView.
Abstract This article reviews the pathological changes in the enamel of permanent mandibular cheek teeth and their sequelae in European roe deer from regions polluted by anthropogenic fluoride emissions. The primary (developmental) changes of fluorotic roe deer enamel are hypomineralization and microstructural aberrations, including enamel hypoplasia ...
Uwe Kierdorf, Horst Kierdorf
wiley   +1 more source

Mitochondrial Dysfunction and Protein Homeostasis in Aging: Insights from a Premature-Aging Mouse Model. [PDF]

Biomolecules
Ross JM, Olson L, Coppotelli G.
europepmc   +1 more source