Results 191 to 200 of about 253,780 (335)

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Correlation analysis between patent ductus arteriosus and bronchopulmonary dysplasia in premature infants. [PDF]

Ital J Pediatr
Luo H, Liu Y, Yan C, Weng B, Zhao L, Cai C.   +5 more
europepmc   +1 more source

A Novel Maturation Equation for Hepatic Clearance Across Preterm, Term Neonates, Children, and Adults: Application to Paracetamol and Its Metabolite

The Journal of Clinical Pharmacology, EarlyView.
Abstract A preterm and term neonate to adult (PTNA) maturation equation was introduced recently to describe the glomerular filtration rate maturation from birth to adulthood for neonates of varying gestational age. This study aims to evaluate the newly developed PTNA equation against common maturation approaches like allometric scaling (AS0.75), the ...
Yunjiao Wu, Swantje Völler, Sebastiaan C. Goulooze, Karel Allegaert, Catherine M. T. Sherwin, Anne van Rongen, Daniëlla W. E. Roofthooft, Sinno H. P. Simons, Dick Tibboel, Robert B. Flint, John N. van den Anker, Catherijne A. J. Knibbe   +11 more
wiley   +1 more source

Pulmonary Hemorrhage in Premature Infants: Pathophysiology, Risk Factors and Clinical Management. [PDF]

Biomedicines
Sahussarungsi S, Lapointe A, Villeneuve A, Hebert A, Nouraeyan N, Lakshminrusimha S, Singh Y, Sabapathy C, Cavallé-Garrido T, Sant'Anna G, Altit G.   +10 more
europepmc   +1 more source

Immunoglobulin A and M levels in premature infants with gastroenteritis [PDF]

, 1971
Panayotis P. Panayotou, C. Papadatos, G. Papaevangelou, D Alexiou, Angeliki Skardoutsou, E. Kourea   +5 more
openalex   +1 more source

Saliva as a TDM matrix and its application in the model‐informed precision dosing

The Journal of Clinical Pharmacology, EarlyView.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu, Yujie Wen, Jinxia Lu, Maobai Liu, Xin Luo, Wei Huang, Helin Xie, Yu Cheng, Hongqiang Qiu, Xuemei Wu   +9 more
wiley   +1 more source

CONTROLLED TRIAL OF INTERMITTENT PHOTOTHERAPY IN THE TREATMENT OF JAUNDICE OF THE PREMATURE INFANT [PDF]

, 1977
Leonord Indyk, Thomas Hegyi, Mark Hiatt, Richard A. Polin, Thomas P. Vogl, L. Stanley James   +5 more
openalex   +1 more source

From PICU to NICU: Extrapolating Meropenem Exposure From Pediatric to Neonatal Intensive Care Patients

The Journal of Clinical Pharmacology, EarlyView.
Abstract We previously developed a population pharmacokinetic (PopPK) model for meropenem in pediatric intensive care unit patients accounting for effect of body size, maturation, and kidney function on clearance. This study aimed to extrapolate meropenem exposure to neonates and young infants using the pediatric PopPK model and to validate the ...
Ronaldo Morales Junior, Tomoyuki Mizuno, Wen Rui Tan, Kei Irie, Sonya Tang Girdwood   +4 more
wiley   +1 more source

Post-Discharge Trajectories of Romanian Premature Infants: A Cross-Sectional Analysis of Associated Factors. [PDF]

Children (Basel)
Rosca I, Dinulescu A, Prejmereanu A, Pavelescu ML, Palcău AC, Popescu DE, Constantin AT.   +6 more
europepmc   +1 more source

Syndrome in Premature Infants Associated with Low Plasma Vitamin E Levels and High Polyunsaturated Fatty Acid Diet

, 1966
H. T. Hassan, Sami A. Hashim, Theodore B. Van Itallie, W. H. Sebrell   +3 more
openalex   +1 more source