Results 121 to 130 of about 256,466 (233)

Frailty in Adults With Down Syndrome: Cognitive, Functional and Biomarker Associations

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Down syndrome (DS) entails widespread age‐related functional decline affecting multiple organ systems, including genetically determined early‐onset Alzheimer disease (DSAD), resulting in an increased vulnerability to frailty early in life.
Georg Nübling, Lena Marth, Katja Sandkühler, Anna Stockbauer, Elisabeth Wlasich, Alexander Jäck, Olivia Wagemann, Julia Kustermann, Steffen Halbgebauer, Hayrettin Tumani, Günter Höglinger, Johannes Levin   +11 more
wiley   +1 more source

An Update on Early‐Onset Breast Cancer: Incidence, Risk Factors, Genetic Testing, and Treatment

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Early‐onset breast cancer presents in patients typically under the age of 40, while very early‐onset breast cancer is usually viewed as breast cancer occurring before the age of 35. Early‐onset breast cancer demonstrates specific molecular properties and has worse outcomes compared to its late‐onset breast cancer counterpart.
Leila Jahangiri
wiley   +1 more source

Interaction of FXTAS Family History and College Degree Attainment Predicts Trajectories of Cognitive and Motor Symptoms in FMR1 Premutation Carrier Women

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 7, Page 451-463, October 2026.
ABSTRACT The present longitudinal study focuses on FMR1 premutation carrier women during midlife and early old age (n = 115). Bringing together the genetic risk factor of a family history of FXTAS and the environmental protective factor of higher education, the goal of the study was to determine how these factors potentially interact to predict self ...
Jinkuk Hong, Leann Smith DaWalt, Jessica Klusek, Elizabeth M. Berry‐Kravis, Marsha Mailick   +4 more
wiley   +1 more source

Factors Associated With Menopause Symptoms: A Systematic Review and Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 11, Page 1967-1985, October 2026.
ABSTRACT Background Menopause, marked by hormonal decline and menstrual cessation, is associated with various symptoms. Socio‐demographic and behavioural factors may influence symptom type and severity. Understanding these associations can inform better symptom management.
Janice Hoang, Kathryn Halliday, Deborah Allen, Wema Meranda Mtika, Eve Tranter, Grace Glover, Lynn Tatnell, Julia Hippisley‐Cox, Carol Coupland, Sarah Hillman, Jennifer Hirst   +10 more
wiley   +1 more source

Association Between Vasomotor Symptoms of Menopause and Retirement: A Prospective Longitudinal Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 11, Page 2044-2053, October 2026.
ABSTRACT Objective To assess the association between vasomotor symptoms of menopause and retirement in Australian women. Design Population‐based cohort study. Setting Secondary analysis of six surveys collected between 1996 and 2010. Population A total of 6928 Australian women, born between 1946 and 1951. Methods Data were obtained from participants in
Biresaw Wassihun Alemu, Michael Waller, Leigh R. Tooth   +2 more
wiley   +1 more source

Premature Menopause and Risk for Cardiovascular Disease-Reply. [PDF]

JAMA, 2020
Honigberg MC, Natarajan P.
europepmc   +1 more source

At Home Detection of Ovarian Health Biomarker in Menstruation Blood

Advanced Materials Technologies, Volume 11, Issue 17, 3 September 2026.
A lateral flow assay enables the detection of anti‐Müllerian hormone directly in unprocessed menstrual blood using silica‐gold nanoshells and smartphone‐assisted machine learning analysis. The platform supports decentralized, user‐operated testing in wearable and dipstick formats, highlighting the potential of menstrual blood as a non‐invasive matrix ...
Lucas Dosnon, Thomas Rduch, Salma Sherif Azer, Inge K. Herrmann   +3 more
wiley   +1 more source

Premature ovarian insufficiency in patients with thyroid-related poly-autoimmunity

Frontiers in Endocrinology
BackgroundAn anticipated menopause is a disquieting health problem; its association with autoimmune disorders has been reported. However, data about the presence of premature ovarian insufficiency (POI) and early menopause (EM) framed in thyroid-related ...
Maria Flavia Bagaglini, Maria Flavia Bagaglini, Ilaria Stramazzo, Ilaria Stramazzo, Matteo Nocito, Poupak Fallahi, Alessandro Antonelli, Maria Giulia Santaguida, Lucilla Gargano, Francesca Ferrari, Enke Baldini, Salvatore Ulisse, Anna Carretti, Marco Centanni, Camilla Virili, Camilla Virili   +15 more
doaj   +1 more source

Anti‐Müllerian Hormone and Metabolic–Hormonal Profiles in Women With and Without Polycystic Ovary Syndrome: A Population‐Based Study

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
In this population‐based study of 883 women, AMH declined less with age in women with PCOS than in healthy women. Higher AMH may protect older healthy women from T2DM but indicates elevated metabolic risk in younger women with PCOS, supporting its role as a life‐course biomarker for metabolic risk stratification.
Fahimeh Ramezani Tehrani, Maryam Mousavi, Marzieh Saei Ghare Naz, Maryam Farahmand, Masoumeh Jorjani, Fatemeh Mahboobifard   +5 more
wiley   +1 more source

Sex and Gender Differences in Physical Activity, Sedentary Behavior, and Sleep During Traumatic Brain Injury Recovery: A Narrative Review

European Journal of Sport Science, Volume 26, Issue 9, September 2026.
ABSTRACT Traumatic brain injury (TBI) is a complex neurological condition with enduring consequences that extend well beyond the initial insult. Once regarded primarily as an acute event, TBI is now increasingly recognized as a chronic disorder associated with cognitive, emotional, and physical impairments.
Goretti España‐Irla, Madeleine Perko, Emma M. Tinney, Mark C. Nwakamma, Martina Anto‐Ocrah, Timothy P. Morris   +5 more
wiley   +1 more source