Results 291 to 300 of about 30,899 (323)
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Genetics of premature ovarian failure
Current Opinion in Obstetrics & Gynecology, 2015To provide an overview on the genetic basis of premature ovarian failure (POF) with specific attention to recently published molecular genetic studies.POF is an insidious cause of female infertility. Despite enormous efforts to understand the genetic pathogenesis, we know almost nothing but Turner syndrome and Fragile X syndrome. The era of genome-wide
Ekrem M, Bilgin, Ertug, Kovanci
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Premature ovarian failure and dehydroepiandrosterone
Fertility and Sterility, 2009Since the first successful birth at our center following treatment with DHEA in a patient with premature ovarian failure (POF), all subsequent patients with POF underwent the same treatment protocol. Receiving very encouraging results (FSH level was decreased in the first five patients and all achieved pregnancy), it was decided to study the action of ...
Leonidas, Mamas, Eudoxia, Mamas
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Premature ovarian failure and pregnancy
Archives of Gynecology and Obstetrics, 2005A case study of a woman with presumed premature menopause is presented.After more than 4 years of premature menopause judged by subjective symptoms, bleeding history, and postmenopausal levels of gonadotropins, a woman conceived spontaneously 2 months after the start of hormone replacement treatment (HRT).
Vandborg, M, Lauszus, F F
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Autoimmunity and premature ovarian failure
Current Opinion in Obstetrics & Gynecology, 2007The different patterns of autoreactivity that may account for the premature infertility observed in patients with premature ovarian failure are described.Animal model studies have detailed fundamental immune dysregulatory patterns that induce ovarian failure in the context of global polyglandular involvement, as well as autoimmune mechanisms that ...
Vincent K, Tuohy, Cengiz Z, Altuntas
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Autoimmune Premature Ovarian Failure
Journal of Obstetrics and Gynaecology, 1995AbstractPremature ovarian failure (POF) may be caused by a variety of factors that result in the depletion of responsive ovarian follicles. There is a increasing body of evidence that suggests an autoimmune etiology in some POF patients. Data in support of an autoimmune etiology include: (1) lymphocytic and plasma cell infiltration of the ovary and ...
J G, Kim +3 more
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Management of premature ovarian failure
Best Practice & Research Clinical Obstetrics & Gynaecology, 2009Premature ovarian failure (POF), a major life-changing condition that affects a significant proportion of young women, remains an enigma and the researcher's minefield. As women increasingly survive childhood cancers due to improved iatrogenic interventions, the number of POF sufferers will inevitably increase.
Nick, Panay, Emmanuel, Kalu
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Pregnancies After Premature Ovarian Failure
Obstetrics & Gynecology, 1986Six women who conceived after a diagnosis of premature ovarian failure are discussed. Two pregnancies occurred while the women were receiving conjugated estrogen therapy, two while taking oral contraceptives, and two women conceived spontaneously. The possible role of exogenous estrogens in sensitizing the granulosa cells to the effect of follicle ...
M M, Alper, E E, Jolly, P R, Garner
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Research on the mechanisms of premature ovarian failure
Journal of the Society for Gynecologic Investigation, 2001As many as 5% of women may experience menopause at or before age 45 (POF). Four causes are known for POF: (1) Genetic. Clear-cut X chromosome deletions, particularly those in the critical region, result in truncation of reproductive lifespan. Creation of a central genetic data bank for women with POF may assist in defining the genetic contribution to ...
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