Results 81 to 90 of about 3,287 (210)

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng   +4 more
wiley   +1 more source

Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000–2024)

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Intrauterine insemination (IUI) is a widely used first‐line fertility treatment, yet its success rates vary considerably. This review synthesizes evidence from peer‐reviewed studies published between 2000 and 2024, including randomized controlled trials, cohort and case–control studies, as well as systematic and narrative reviews identified ...
Kasuni Akalanka
wiley   +1 more source

Causal effects of reproductive traits on cognitive function: A two‐sample and multivariable mendelian randomization study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Potential associations between reproductive traits and cognitive function have been discovered; however, the results are inconsistent, and the causalities are unclear. This study utilized Mendelian randomization (MR) analysis to assess the causal impact of reproductive traits on cognitive function.
Xia Wang, Yunyun Guo
wiley   +1 more source

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

open access: yesiMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu   +6 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

open access: yesiNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little   +12 more
wiley   +1 more source

The Functions and Implications of MicroRNAs in Premature Ovarian Insufficiency

open access: yesMolecular Genetics & Genomic Medicine
Background Premature ovarian insufficiency (POI) is a condition in women characterized by the premature decline of ovarian function before age 40, evident through menstrual irregularities such as amenorrhea or oligomenorrhea, elevated FSH levels ...
Hui Gao, Xi‐Xia Cao, Hua Hua, Hui Zhu
doaj   +1 more source

Global Health Governance Cannot Keep Relying on the Development‐Goals Model to Effectively Address Health Inequalities Around the World

open access: yesSustainable Development, EarlyView.
ABSTRACT The Sustainable Development Goals (SDGs) are nearing their end in 2030, and it is highly unlikely that many of the SDGs would be met by the target date. This calls for the urgent need for an upgraded approach or a new strategy from the “development‐goals” model.
Funom Theophilus Makama
wiley   +1 more source

A Review of the Types of Chemotherapy Drugs Used to Induce Premature Ovarian Failure in Mice [PDF]

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: The most common complication of chemotherapy is infertility due to premature ovarian failure (POF). POF is defined as the loss of normal ovarian function before age 40, characterized by increased gonadotropin levels, decreased estradiol ...
Negar Pouladvand   +4 more
doaj  

Successful Pregnancies Following Hormone Replacement Therapy in a Patient with Premature Ovarian Failure: A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Premature ovarian failure is a serious life-changing condition that affects young women, remains an enigma and the researcher’s challenge. Spontaneous pregnancy in a patient with POF is uncommon.
SUNIL KUMAR K.S.   +2 more
doaj  

FRAXA premutations are not a cause of familial premature ovarian failure [PDF]

open access: bronze, 1999
Anna Marozzi   +5 more
openalex   +1 more source

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