Results 51 to 60 of about 173,400,903 (286)

Premature Rupture of Membranes and Severe Weather Systems

Frontiers in Physiology, 2020
There has long been anecdotal evidence of early labor and delivery in severe weather events leading to preterm birth. In particular, significant barometric pressure changes are associated with hurricanes and bomb cyclones. Some authors have related these
Mackenzie L. Wheeler, Michelle L. Oyen
doaj   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

Advanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann, Adam Brooks Goodman, Myddelton C. Parker, Mark Garren, Ji Eun Park, Chad Schmiedt, Hitesh Handa, Elizabeth J. Brisbois   +7 more
wiley   +1 more source

Normal and premature rupture of fetal membranes at term delivery differ in regional chemotactic activity and related chemokine/cytokine production

, 2013
A gradient of immunological mediators exists in the fetal membranes from the periplacental zone (PZ) to the rupture zone (RZ) at term delivery (rupture of fetal membranes [ROM]).
Gomez-Lopez, Nardhy Yadira, Andrew P. Lobb, Lobb, Andrew Peter, Felipe Vadillo-Ortega, Hernandez-Santiago, Susana, Nardhy Gomez-Lopez, Susana Hernandez-Santiago, Vadillo-Ortega, Felipe, David M. Olson, Olson, David M.   +9 more
core   +1 more source

In Situ Bioorthogonal Synthesis of PROTACs via Dual‐Responsive Cleavage for Synergistic Photo‐Immunotherapy

Advanced Science, EarlyView.
A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian, Jiasha Wu, Fusheng Xu, Yan Zuo, Huaxing Shen, Rui Ji, Luyi Wang, Na Li, Yanting Sun, Yongsheng Yu, Yejiao Shi, Honggang Hu, Feng Xu, Dan Huang, Xiaochun Hu   +14 more
wiley   +1 more source

Associations between the size and duration of asymptomatic subchorionic hematoma and pregnancy outcomes in women with singleton pregnancies

BMC Pregnancy and Childbirth, 2023
Background The purpose of this study was to investigate the relationship between the size and duration of asymptomatic subchorionic hematoma and pregnancy outcomes in women with singleton pregnancies.
Shuangjia Pan, Yehui Lan, Yujia Zhou, Baoyi Chen, Feifei Zhou, Dongru Dai, Ying Hua   +6 more
doaj   +1 more source

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

Advanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang, Yuan Liu, Huan Peng, Yu Ni, Zhengqiao Jiang, Chenxuan Yu, Xincheng Zhang, Huayu Kang, Yanchao Liu, Juan Chen, Kai Zhao, Lin Han, Xin Zou, Kai Shu, Xiaochuan Wang, Jian‐Zhi Wang, Ting Lei, Chao Gan, Jianfeng Liu, Huaqiu Zhang   +19 more
wiley   +1 more source

Functional Genomics of Healthy and Pathological Fetal Membranes

Frontiers in Physiology, 2020
Premature preterm rupture of membranes (PPROM), rupture of fetal membranes before 37 weeks of gestation, is the leading identifiable cause of spontaneous preterm births.
Sarah J. Cunningham, Sarah J. Cunningham, Sarah J. Cunningham, Sarah J. Cunningham, Liping Feng, Terrence K. Allen, Timothy E. Reddy, Timothy E. Reddy, Timothy E. Reddy, Timothy E. Reddy   +9 more
doaj   +1 more source

Logistic regression results for fetal single locus allele frequencies among cases and controls and association with preterm premature rupture of membranes.

, 2018
Logistic regression results for fetal single locus allele frequencies among cases and controls and association with preterm premature rupture of membranes.
Caroline Marrs (5233916), Ramkumar Menon (201971), Scott Williams (27584), Kevin Chesmore (5233913)   +3 more
core   +1 more source

Lipopolysaccharide induces nitric oxide synthase expression and platelet-activating factor increases nitric oxide production in human fetal membranes in culture [PDF]

, 2004
Platelet-activating factor and nitric oxide may be involved in the initiation of human labour as inflammatory mediators. The aim of this study was to test whether platelet-activating factor and lipopolysaccharide were able to induce nitric oxide synthase
Damian J Murphy, Dunmore, Simon J., Murphy Damian J, Carson Ray J, Rodrigo, Nalinda, Seyffarth Gunter, Nelson, Paul N., Dunmore Simon J, Simon J Dunmore, Nalinda Rodrigo, Carson, Ray J., Seyffarth, Gunther, Rodrigo Nalinda, Paul N Nelson, Murphy, Damian J., Nelson Paul N, Gunter Seyffarth, Ray J Carson   +17 more
core   +1 more source

Why Do the Fetal Membranes Rupture Early after Fetoscopy? A Review [PDF]

, 2021
Iatrogenic preterm premature rupture of the fetal membranes (iPPROM) remains the Achilles' heel of keyhole fetal surgery (fetoscopy) despite significant efforts in preclinical models to develop new therapies.
Crossley, Kelly J., Ryan Hodges, Amberg, Benjamin J., Kelly Crossley, Hodges, Ryan J., Benjamin Amberg, P.L.J. (Philip) Dekoninck, Hooper, Stuart B., Stuart B. Hooper, Dekoninck, Philip L.J., Karyn Rodgers, Rodgers, Karyn A., Ryan J. Hodges, Kelly J. Crossley, Karyn A. Rodgers, Benjamin J. Amberg, Philip L.J. DeKoninck   +16 more
core   +1 more source