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The pathobiology of premature rupture of membranes
Seminars in Perinatology, 1996Premature rupture of membranes arises from what are likely multifaceted and multistep pathogenic pathways. Pathophysiological processes may involve both endogenous and exogenous fetal and maternal factors. This article reviews and analyzes information regarding, first, the form and function of fetal membranes; second, how membranes physically fail ...
J I, French, J A, McGregor
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Preterm premature rupture of the membranes
Obstetrics & Gynecology, 2003Preterm premature rupture of membranes (PROM) affects over 120,000 pregnancies annually in the United States and is associated with significant maternal, fetal, and neonatal risk. Management of PROM requires an accurate diagnosis as well as evaluation of the risks and benefits of continued pregnancy or expeditious delivery.
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The Etiology of Premature Rupture of the Membranes
Clinical Obstetrics and Gynecology, 1998The etiology of PROM is multifactorial. It is clear that maternal enzymes, maturational and mechanical forces, chorionicamniotic membrane phospholipid content, collagen disruption, amniotic cell cytokines induced by fetal signals, and bacterial phospholipases and collagenases all play major and interrelated roles.
W J, Polzin, K, Brady
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Management of premature rupture of membranes
Clinics in Perinatology, 2001The management of patients with PROM, regardless of gestational age, remains controversial. Generally, when patients are in labor, have infection, or there is irreversible fetal distress, there are few options other than delivery. For those not in labor, especially in premature gestational ages, the complexities of the many combinations of decisions to
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The Microbiology of Premature Rupture of the Membranes
Clinical Obstetrics and Gynecology, 1986The foregoing discussions bring to mind several salient facts: Although numerous barriers to infection exist, this aspect is understood incompletely. Conclusions on the pathogenicity or nonpathogenicity of certain organisms are often made from studies with very small numbers of patients, or in very specific patient populations.
J M, Miller, J G, Pastorek
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Preterm Premature Rupture of Membranes
Obstetrical & Gynecological Survey, 1993Although the etiology of preterm premature rupture of membranes (PPROM) is probably multifactorial, recent literature has indicated that infectious processes may play an important role. The management of PPROM is still controversial, requiring individualization of care for each patient. Expectant management is increasingly advocated.
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INTRODUCTION TO PREMATURE RUPTURE OF MEMBRANES
Obstetrics and Gynecology Clinics of North America, 1992PROM is associated with controversies in diagnosis, management, and prognosis. The lack of a gold standard to confirm PROM makes it difficult to determine which diagnostic tool is the best and most reliable. It appears that the older methods of confirming PROM, which depend on properties inherent to amniotic fluid, are the best tools available today ...
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Premature Rupture of the Fetal Membranes
New England Journal of Medicine, 1998The membranes surrounding the amniotic cavity are composed of the amnion and the chorion, which are closely adherent layers consisting of several cell types, including epithelial cells, mesenchymal cells, and trophoblast cells, embedded in a collagenous matrix.
S, Parry, J F, Strauss
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Midtrimester premature rupture of the membranes
Seminars in Perinatology, 1996Midtrimester premature rupture of the membranes is an uncommon adverse complication of pregnancy with an occurrence of approximately 0.65%. Significant perinatal and maternal morbidity includes pulmonary hypoplasia, restriction deformities, and sequelae of prematurity as well as maternal chorioamnionitis and endometritis. Moreover, 31% of survivors are
J L, Schucker, B M, Mercer
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Premature Rupture of the Membranes and Ascending Infection
Obstetrical & Gynecological Survey, 1982Summary. The association of premature rupture of the membranes (PROM) and ascending infection was investigated in 15 women. Bacteriological, histological and immunofluorescence methods were used to study infection at various levels in the birth canal.
G R, Evaldson, A S, Malmborg, C E, Nord
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