Results 201 to 210 of about 79,128 (273)

In silico predictions of action potential propagation in doxorubicin cardiotoxicity: A parametric study using preclinical 3D magnetic resonance imaging‐based fibrotic left ventricle models

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the study's methodology and key findings. In a preclinical swine model, doxorubicin administration induced cardiotoxicity, characterized by diffuse fibrotic remodelling and altered electrical function, as assessed by magnetic resonance (MR) imaging and electrophysiological mapping.
Javier Villar‐Valero   +7 more
wiley   +1 more source

A subtype of idiopathic ventricular fibrillation and its relevance to catheter ablation and genetic variants

open access: yesHeartRhythm Case Reports, 2017
Takahiko Nishiyama, MD   +5 more
doaj   +1 more source

Sildenafil helps the beat go on

open access: yes
Experimental Physiology, EarlyView.
Jules C. Hancox
wiley   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière   +6 more
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies.
Silvia Marchianò   +18 more
wiley   +1 more source

Developmental Brain Age Estimation From MRI Data: A Systematic Review of Deep Learning Approaches and Open Datasets

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 3, Page 650-671, March 2026.
ABSTRACT Brain age is an emerging concept that reflects complex, time‐dependent changes in brain structure, identifying departures from expected neurodevelopmental patterns. In the developing brain, accurate MRI‐based age estimation is a quantitative biomarker for detecting atypical neurodevelopment, facilitating early diagnosis, guiding clinical ...
Hosna Asma ull   +3 more
wiley   +1 more source

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